ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR988/004/ERR9888084/ERR9888084_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR989/001/ERR9896531/ERR9896531.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR989/002/ERR9896532/ERR9896532.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR989/005/ERR9890755/ERR9890755_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR988/004/ERR9888084/ERR9888084_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR989/003/ERR9896533/ERR9896533.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR989/005/ERR9890755/ERR9890755_2.fastq.gzprimary200OKGenomicsMax Planck Institute for Evolutionary Anthropologyhttps://www.ebi.ac.uk/ena/browser/view/PRJEB53912The Greek colony of Himera lasted from 648 BCE until its destruction by Carthage in 409 BCE and is one of the most extensively excavated cities from the Greek archaic / classical world. The skeletal remains belonging to a single male individual showing morphological indications of dwarfism were found in 2009 in the Western Necropolis of Himera in Sicily. Genetic analysis of genome-wide data generated for this individual confirmed the diagnosis of achondroplasia. This individual had entirely Anatolian ancestry.ENA"Chondrodystrophia" EXACT [MTHICD9_2006:756.4], "Achondroplasia (disorder)" EXACT [SNOMEDCT_2005_07_31:86268005], Skeleton Skin Brain Syndrome, Skeleton-Skin-Brain Syndromes, set of bones of body, Skeleton-Skin-Brain, "Achondroplastic physique" EXACT [SNOMEDCT_2005_07_31:190584003], SADDAN Dysplasia, SADDAN Dysplasias, determination, Skeleton-Skin-Brain Syndrome, skeleton, Skeletons, Set of all bones, "Achondroplastic dwarf" EXACT [SNOMEDCT_2005_07_31:205467007], Dysplasias, Dysplasia, Severe Achondroplasia with Developmental Delay and Acanthosis Nigricans, ACH, skeleton component, Syndromes, set of all bones, "osteosclerosis congenita" EXACT [CSP2005:2715-2940], SADDAN, "achondroplasia" EXACT [CSP2005:1849-0171]., chemical analysis, Syndrome, "Achondroplastic dwarf" EXACT [SNOMEDCT_2005_07_31:268273004], Achondroplasias, Achondroplasia, Achondroplastic dwarfism, With Developmental Delay And Acanthosis Nigricans, assay, "Achondroplastic physique (finding)" EXACT [SNOMEDCT_2005_07_31:248299001], SADDANs, Severe, Skelettsystem, Skeleton (in vivo), Set of bones of bodyfalseGenomic analysis of 5th century BCE skeleton from Himera, Sicily, reveals confirmed case of achondroplasiaAn achondroplastic individual from 5 th century BCE Himera, Sicily2024-06-042024-06-04PRJEB53912