ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/084/ERR10668484/ERR10668484_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/006/ERR10671806/ERR10671806_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/018/ERR10671818/ERR10671818.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/018/ERR10671818/ERR10671818_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/017/ERR10671817/ERR10671817_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/007/ERR10671807/ERR10671807.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/084/ERR10668484/ERR10668484.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/019/ERR10671819/ERR10671819_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/072/ERR10668072/ERR10668072_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/007/ERR10671807/ERR10671807_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/017/ERR10671817/ERR10671817.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/010/ERR10667610/ERR10667610_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/006/ERR10671806/ERR10671806.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/006/ERR10671806/ERR10671806_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/018/ERR10671818/ERR10671818_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/010/ERR10667610/ERR10667610_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/072/ERR10668072/ERR10668072_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/005/ERR10671805/ERR10671805_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/005/ERR10671805/ERR10671805.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/007/ERR10671807/ERR10671807_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/005/ERR10671805/ERR10671805_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/084/ERR10668484/ERR10668484_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/019/ERR10671819/ERR10671819_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/017/ERR10671817/ERR10671817_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/072/ERR10668072/ERR10668072.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR106/019/ERR10671819/ERR10671819.fastq.gzprimary200OKGenomicsIGB-EBIhttps://www.ebi.ac.uk/ena/browser/view/PRJEB58148Profilin 1 –encoded by PFN1– is a small actin-binding protein with a tumour suppressive role in various adenocarcinomas and pagetic osteosarcomasd. Fix and live cell imaging showed that Profilin 1 inactivation results in multiple mitotic defects. Low-pass whole-genome sequencing analysis on eight Pfn1-KO MC3T3 cells highlighted frequent copy number alterations involving multiple chromosomes.ENAfalseCopy number analysis of Profilin 1-deficient MC3T3 cellsProfilin 1 deficiency drives copy number alterations in MC3T3 cells2023-01-032023-01-03PRJEB58148