ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/059/ERR12081959/ERR12081959_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/055/ERR12081955/ERR12081955_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/060/ERR12081960/ERR12081960_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/058/ERR12081958/ERR12081958_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/057/ERR12081957/ERR12081957_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/054/ERR12081954/ERR12081954_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/057/ERR12081957/ERR12081957_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/056/ERR12081956/ERR12081956_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/058/ERR12081958/ERR12081958_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/061/ERR12081961/ERR12081961_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/055/ERR12081955/ERR12081955_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/054/ERR12081954/ERR12081954_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/060/ERR12081960/ERR12081960_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/056/ERR12081956/ERR12081956_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/059/ERR12081959/ERR12081959_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR120/061/ERR12081961/ERR12081961_1.fastq.gzprimaryOK200GenomicsLudwig-Maximilians-Universität, Munich Faculty of Biology Anthropology and Human GenomicsEuropean Bioinformatics Institutehttps://www.ebi.ac.uk/ena/browser/view/PRJEB66457ArrayExpressATAC-seq samples from 2 species and 2 cell types were generated to study cis-regulatory element evolution. Briefly, previously generated urinary stem cell derived iPS-cells (Homo sapiens) of 2 human individuals and fibroblast derived cynomolgus macaque iPSCs (Macaca fascicularis) of 2 individuals (Geuder et al. 2021) were differentiated to neural progenitor cells via dual-SMAD inhibition as three-dimensional aggregation culture (Chambers et al. 2009 Ohnuki et al. 2014). The NPC lines were cultured in NPC proliferation medium and passaged 2 - 4 times until they were dissociated and subjected to ATAC-seq together with the respective iPSC clones. ATAC-seq libraries were generated using the Omni-ATAC protocol (Corces et al. 2017) with minor modifications.ENAfalseATAC-seq of human (Homo sapiens) and cynomolgus macaque (Macaca fascicularis) iPSC and iPSC-derived NPC cell linesATAC-seq of human (Homo sapiens) and cynomolgus macaque (Macaca fascicularis) iPSC and iPSC-derived NPC cell lines2023-10-252023-10-25PRJEB66457