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Bioinformatics Institute","Department of Cell and Development Biology, Faculty of Medicine, Tel Aviv University, Israel"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJEB71331"],"broker_name":["ArrayExpress"],"long_description":["To elucidate the role of pericytic cytokines in islet inflammation, we interfered with the expression of MyD88, a key modulator of the IL1R1/TLR pathway, in pericytes using transgenic mice (Nkx3.2-Cre MyD88 flox/flox) . To determine the impact on islet immune cells, we isolated CD45+ cells from the islets of both non-transgenic and Myd88-deficient mice via MACS, pooling samples from 4-5 littermate male mice. Additionally, unsorted islet cells from the same pool were included to meet the cell number requirements for sample preparation using X10 genomics."],"repository":["ENA"],"description_synonyms":["myd88, 3.4.22.-, Single-Cell RNAseq, Sc RNAseq, Laboratory, dMyD88, Single Cell Gene Expression Profiling, Mus domesticus, Myd88F, ScRNA seq, mini-ICE, CASP-14, Islets, House Mouse, Pancreatic Islet, single-cell transcriptome sequencing, single-cell RNA-seq, House, dMyd88, Mus musculus domesticus, Seqs, Langerhans Islands, Analysis, Mice, Seq, XMyD88, Endocrine Pancreas, pericapillary cell, MYD88D, ScRNAseq, Single-Cell Transcriptome Analysis, Endocrine, Analyses, Swiss, perithelial cell, Swiss Mice, Islet Cells, Single Cell RNAseq, Single Cell RNA Seq, CG2078, Transcriptome Analysis, RNA Seq, ScRNA-seq, perivascular cell, DmMyD88, TG, RNA-Seq, house mouse, MYD88, Single-Cell RNA-Seq, MyD88, Single-Cell Gene Expression Profiling, mouse, scRNA-seq, DmMyd88, Single Cell Gene Expression Analysis, Nesidioblasts, Single-Cell, Cell, Single Cell Transcriptome Analysis, Sc-RNAseq, single cell RNA sequencing, Mus, Islet, Mini-ICE, Pancreatic, Islands of Langerhans, Kra, Mus musculus., Pericyte, Mus musculus, Single-Cell RNA, Single-Cell Transcriptome Analyses, Caspase-14 subunit p10, mice, EP(2)2535, Swiss Mouse, Nesidioblast, House Mice, Caspase-14 subunit p19, Pancreatic Islets, MICE, Single-Cell RNA Seq, kra, Transcriptome Analyses, Pancreas, DMMYD88, Rouget, domesticus, Laboratory Mice, Rouget Cells, LD20892, adventitial cell, DmelCG2078, Single-Cell Transcriptome, Langerhans Islets, Islet Cell, RNAseq, Cells, Mouse, Laboratory Mouse, myd88d"],"name_synonyms":["myd88, 3.4.22.-, Single-Cell RNAseq, Sc RNAseq, Laboratory, dMyD88, Single Cell Gene Expression Profiling, Mus domesticus, Myd88F, ScRNA seq, mini-ICE, CASP-14, Islets, House Mouse, Pancreatic Islet, single-cell transcriptome sequencing, single-cell RNA-seq, House, dMyd88, Mus musculus domesticus, Seqs, Langerhans Islands, Analysis, Mice, Seq, XMyD88, Endocrine Pancreas, pericapillary cell, MYD88D, ScRNAseq, Single-Cell Transcriptome Analysis, Endocrine, Analyses, Swiss, perithelial cell, Swiss Mice, Islet Cells, Single Cell RNAseq, Single Cell RNA Seq, CG2078, Transcriptome Analysis, RNA Seq, ScRNA-seq, perivascular cell, DmMyD88, TG, RNA-Seq, house mouse, MYD88, Single-Cell RNA-Seq, MyD88, Single-Cell Gene Expression Profiling, mouse, scRNA-seq, DmMyd88, Single Cell Gene Expression Analysis, Nesidioblasts, Single-Cell, Cell, Single Cell Transcriptome Analysis, Sc-RNAseq, single cell RNA sequencing, Mus, Islet, Mini-ICE, Pancreatic, Islands of Langerhans, Kra, Mus musculus., Pericyte, Mus musculus, Single-Cell RNA, Single-Cell Transcriptome Analyses, Caspase-14 subunit p10, mice, EP(2)2535, Swiss Mouse, Nesidioblast, House Mice, Caspase-14 subunit p19, Pancreatic Islets, MICE, Single-Cell RNA Seq, kra, Transcriptome Analyses, Pancreas, DMMYD88, Rouget, domesticus, Laboratory Mice, Rouget Cells, LD20892, adventitial cell, DmelCG2078, Single-Cell Transcriptome, Langerhans Islets, Islet Cell, RNAseq, Cells, Mouse, Laboratory Mouse, myd88d"],"additional_accession":[]},"is_claimable":false,"name":"scRNA-seq of mouse pancreatic islets from non-transgenic and pericyte MyD88-mutated mice","description":"scRNA-seq of mouse pancreatic islets from non-transgenic and pericyte MyD88-mutated mice","dates":{"last_updated":"2023-12-31","first_public":"2023-12-31"},"accession":"PRJEB71331","cross_references":{}}