ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/005/SRR25707005/SRR25707005_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/007/SRR25707007/SRR25707007_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/010/SRR25707010/SRR25707010_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/009/SRR25707009/SRR25707009_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/006/SRR25707006/SRR25707006_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/009/SRR25707009/SRR25707009_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/010/SRR25707010/SRR25707010_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/006/SRR25707006/SRR25707006_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/008/SRR25707008/SRR25707008_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/005/SRR25707005/SRR25707005_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/008/SRR25707008/SRR25707008_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR257/007/SRR25707007/SRR25707007_1.fastq.gzprimaryOK200GenomicsDepartment of Pediatrics, Kyushu Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA1007593Mus musculusxref:PubMed:39048611Pathogenic variations in GNAO1 are associated with developmental and epileptic encephalopathy (DEE). To understand molecular mechanisms underlying GNAO1-associated DEE, we performed a transcriptomic analysis (RNA sequencing) on Neuro2a cells after siRNA-mediated silencing of Gnao1. Overall design: Comparative analysis of Neuro2a cell lines treated with siRNA to Gnao1 (n = 3) and those with control siRNA (n = 3). Bulk-prepared RNA was used for RNA sequencing. Both RSEM and rMATS algorithms were used.ENAfalseRegulatory role of Gnao1 in neuronal differentitationRegulatory role of Gnao1 in neuronal differentitation2025-09-242024-08-04PRJNA1007593GSE2412581009039048611