{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Translational Neuroimmunology, Neurology, Mayo Clinic"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA1009857"],"scientific_name":["Mus musculus"],"tag":["xref:PubMed:37676734"],"long_description":["Ribotag mice were crossed to synapsin-CRE mice to induce expression of HA-tagged Rpl22 subunits in neurons. Mice were fed cuprizone to induce demyelination or were induced with MOG(35-55) peptide to establish experimental autoimmune encephalomyelitis. Brain was collected from EAE mice at 18 days after induction (peak disease) and from cuprizone-fed mice at 6 weeks on chow. Brain was also collected from unmanipulated control mice fed normal chow. Brain lysates were immunoprecipated with anti-HA antibody to isolated neuron-specific polyribosomes. RNA was extracted from the IP and analyzed by Affymetrix GeneChip® Mouse Gene 2.0 ST Arrays. Overall design: 4 control mice vs 6 EAE mice vs 6 cuprizone mice"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Neuron-specific RNA responses to EAE and cuprizone","description":"Neuron-specific RNA responses to EAE and cuprizone","dates":{"last_updated":"2025-09-24","first_public":"2023-09-08"},"accession":"PRJNA1009857","cross_references":{"GEO":["GSE241781"],"taxon":["10090"],"PubMed":["37676734"]}}