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Institute of Coastal Zone Research, Chinese Academy of Scienceshttps://www.ebi.ac.uk/ena/browser/view/PRJNA1013748The predictive molecular model of the microbial-dependent delay of strobilation was elucidated that symbiotic cyanobacteria eliminated by antibiotics in the polyp stage enable to synthesize the retinal through enzymatic pathways, hence triggering the chain reaction in the retinoic acid signaling cascade that drives the strobilation of Aurelia. Remarkably, we observed that microbiota regulates nematocyte development and differentiation during the polyp-to-medusa transition, which in turn affects jellyfish fitness-related feeding and growth.xref:EuropePMC:PMC10988111xref:EuropePMC:PMC10730743ENAfalseThe transcriptomics data generated in life cycle transition of jellyfish2023-09-092023-09-09PRJNA1013748