ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/004/SRR26342204/SRR26342204.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/021/SRR26342221/SRR26342221.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/074/SRR26342074/SRR26342074.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/091/SRR26342091/SRR26342091.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/039/SRR26342339/SRR26342339.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/056/SRR26342356/SRR26342356.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/073/SRR26342373/SRR26342373.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/021/SRR26342321/SRR26342321.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/004/SRR26342304/SRR26342304.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/004/SRR26342104/SRR26342104.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/069/SRR26342169/SRR26342169_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/056/SRR26342256/SRR26342256.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/045/SRR26341945/SRR26341945.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/090/SRR26342390/SRR26342390_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/022/SRR26342022/SRR26342022.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/090/SRR26342290/SRR26342290.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/097/SRR26341997/SRR26341997.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/091/SRR26342291/SRR26342291.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/039/SRR26342139/SRR26342139.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/010/SRR26341910/SRR26341910_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/090/SRR26342190/SRR26342190.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/000/SRR26341900/SRR26341900_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/098/SRR26341998/SRR26341998.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/061/SRR26341961/SRR26341961.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/002/SRR26341902/SRR26341902_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/039/SRR26342039/SRR26342039.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/091/SRR26342191/SRR26342191.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/090/SRR26342090/SRR26342090.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/039/SRR26342239/SRR26342239.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/003/SRR26342203/SRR26342203.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/055/SRR26342355/SRR26342355.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/062/SRR26341962/SRR26341962.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/003/SRR26342303/SRR26342303.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/080/SRR26341980/SRR26341980.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/055/SRR26342255/SRR26342255.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/072/SRR26342272/SRR26342272.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/075/SRR26342075/SRR26342075.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/023/SRR26342023/SRR26342023.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/092/SRR26342192/SRR26342192.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/058/SRR26342058/SRR26342058.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/006/SRR26342006/SRR26342006.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/063/SRR26341963/SRR26341963.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/022/SRR26342222/SRR26342222.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/056/SRR26342056/SRR26342056.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/073/SRR26342073/SRR26342073.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/005/SRR26342405/SRR26342405.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/005/SRR26342205/SRR26342205.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/020/SRR26342220/SRR26342220.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/038/SRR26342338/SRR26342338.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/003/SRR26342003/SRR26342003.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/075/SRR26342275/SRR26342275.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/021/SRR26342021/SRR26342021.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/074/SRR26342274/SRR26342274.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/057/SRR26342257/SRR26342257.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/093/SRR26342393/SRR26342393_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/004/SRR26342004/SRR26342004.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/000/SRR26342400/SRR26342400_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/073/SRR26342273/SRR26342273.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/037/SRR26342337/SRR26342337.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/007/SRR26341907/SRR26341907_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/081/SRR26341981/SRR26341981.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/006/SRR26342206/SRR26342206.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/072/SRR26342172/SRR26342172_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/058/SRR26342258/SRR26342258.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/057/SRR26342057/SRR26342057.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/005/SRR26342005/SRR26342005.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/020/SRR26342020/SRR26342020.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/072/SRR26342072/SRR26342072.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/007/SRR26342007/SRR26342007.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/041/SRR26342041/SRR26342041.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/024/SRR26342024/SRR26342024.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/093/SRR26342293/SRR26342293.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/091/SRR26342391/SRR26342391_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/076/SRR26342276/SRR26342276.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/023/SRR26342323/SRR26342323.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/006/SRR26342306/SRR26342306.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/059/SRR26342259/SRR26342259.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/006/SRR26341906/SRR26341906_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/064/SRR26341964/SRR26341964.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/089/SRR26342289/SRR26342289.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/042/SRR26341942/SRR26341942.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/001/SRR26342301/SRR26342301.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/071/SRR26342171/SRR26342171_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/059/SRR26342159/SRR26342159.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/055/SRR26342055/SRR26342055.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/093/SRR26342193/SRR26342193.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/037/SRR26342137/SRR26342137.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/026/SRR26341926/SRR26341926.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/019/SRR26342319/SRR26342319.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/001/SRR26342201/SRR26342201.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/048/SRR26341948/SRR26341948.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/099/SRR26341899/SRR26341899_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/037/SRR26342037/SRR26342037.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/041/SRR26342341/SRR26342341.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/002/SRR26342202/SRR26342202.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/055/SRR26342155/SRR26342155.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/002/SRR26342302/SRR26342302.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/054/SRR26342054/SRR26342054.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/011/SRR26341911/SRR26341911_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/003/SRR26342403/SRR26342403_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/077/SRR26342177/SRR26342177.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/038/SRR26342138/SRR26342138.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/047/SRR26341947/SRR26341947.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/025/SRR26341925/SRR26341925.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/008/SRR26342008/SRR26342008.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/070/SRR26342270/SRR26342270_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/040/SRR26342340/SRR26342340.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/076/SRR26342176/SRR26342176.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/038/SRR26342038/SRR26342038.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/092/SRR26342292/SRR26342292.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/054/SRR26342154/SRR26342154.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/070/SRR26342170/SRR26342170_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/088/SRR26342288/SRR26342288.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/022/SRR26342322/SRR26342322.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/077/SRR26342277/SRR26342277.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/094/SRR26342294/SRR26342294.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/058/SRR26342158/SRR26342158.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/075/SRR26342175/SRR26342175.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/046/SRR26341946/SRR26341946.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/029/SRR26341929/SRR26341929.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/025/SRR26342025/SRR26342025.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/000/SRR26342200/SRR26342200.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/027/SRR26341927/SRR26341927.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/024/SRR26342324/SRR26342324.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/036/SRR26342036/SRR26342036.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/041/SRR26341941/SRR26341941.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/040/SRR26342040/SRR26342040.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/005/SRR26342305/SRR26342305.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/020/SRR26342320/SRR26342320.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/043/SRR26341943/SRR26341943.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/060/SRR26341960/SRR26341960.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/092/SRR26342392/SRR26342392_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/056/SRR26342156/SRR26342156.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/008/SRR26342308/SRR26342308.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/073/SRR26342173/SRR26342173.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/026/SRR26342026/SRR26342026.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/044/SRR26341944/SRR26341944.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/097/SRR26342397/SRR26342397_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/043/SRR26342043/SRR26342043.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/042/SRR26342042/SRR26342042.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/019/SRR26342019/SRR26342019.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/057/SRR26342157/SRR26342157.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/095/SRR26342295/SRR26342295.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/028/SRR26341928/SRR26341928.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/007/SRR26342307/SRR26342307.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/035/SRR26342035/SRR26342035.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/060/SRR26342260/SRR26342260.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/009/SRR26342209/SRR26342209.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/026/SRR26342226/SRR26342226.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/040/SRR26341940/SRR26341940.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/004/SRR26341904/SRR26341904_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/092/SRR26342392/SRR26342392_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/043/SRR26342243/SRR26342243.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/052/SRR26342052/SRR26342052.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/087/SRR26342287/SRR26342287.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/043/SRR26342343/SRR26342343.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/099/SRR26342399/SRR26342399_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/075/SRR26341975/SRR26341975.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/060/SRR26342160/SRR26342160.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/009/SRR26342309/SRR26342309.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/000/SRR26342000/SRR26342000.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/017/SRR26342417/SRR26342417.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/087/SRR26342387/SRR26342387.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/074/SRR26342174/SRR26342174_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/026/SRR26342126/SRR26342126.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/023/SRR26341923/SRR26341923.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/078/SRR26342178/SRR26342178.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/096/SRR26342096/SRR26342096.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/042/SRR26342342/SRR26342342.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/009/SRR26342009/SRR26342009.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/004/SRR26342404/SRR26342404_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/025/SRR26342325/SRR26342325.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/093/SRR26341993/SRR26341993.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/061/SRR26342161/SRR26342161.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/076/SRR26341976/SRR26341976.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/086/SRR26342386/SRR26342386.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/069/SRR26342369/SRR26342369.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/071/SRR26342171/SRR26342171_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/092/SRR26341992/SRR26341992.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/026/SRR26342326/SRR26342326.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/025/SRR26342225/SRR26342225.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/053/SRR26342053/SRR26342053.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/069/SRR26342269/SRR26342269.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/009/SRR26342109/SRR26342109.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/042/SRR26342142/SRR26342142.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/025/SRR26342125/SRR26342125.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/091/SRR26341991/SRR26341991.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/071/SRR26342271/SRR26342271_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/024/SRR26341924/SRR26341924.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/074/SRR26341974/SRR26341974.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/057/SRR26341957/SRR26341957.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/008/SRR26341908/SRR26341908_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/022/SRR26341922/SRR26341922.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/008/SRR26342208/SRR26342208.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/016/SRR26342416/SRR26342416.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/070/SRR26342070/SRR26342070.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/097/SRR26342197/SRR26342197.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/027/SRR26342327/SRR26342327.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/061/SRR26342361/SRR26342361.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/000/SRR26342100/SRR26342100.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/015/SRR26342415/SRR26342415.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/095/SRR26342195/SRR26342195.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/028/SRR26342128/SRR26342128.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/027/SRR26342127/SRR26342127.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/044/SRR26342144/SRR26342144.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/071/SRR26342071/SRR26342071.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/096/SRR26342196/SRR26342196.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/079/SRR26342179/SRR26342179.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/059/SRR26341959/SRR26341959.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/094/SRR26342194/SRR26342194.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/060/SRR26342360/SRR26342360.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/007/SRR26342207/SRR26342207.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/088/SRR26342388/SRR26342388.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/001/SRR26341901/SRR26341901_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/021/SRR26341921/SRR26341921.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/043/SRR26342143/SRR26342143.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/044/SRR26342344/SRR26342344.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/058/SRR26341958/SRR26341958.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/073/SRR26341973/SRR26341973.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/067/SRR26342367/SRR26342367.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/098/SRR26342198/SRR26342198.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/069/SRR26342169/SRR26342169_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/099/SRR26342399/SRR26342399_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/062/SRR26342362/SRR26342362.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/002/SRR26342002/SRR26342002.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/045/SRR26342345/SRR26342345.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/084/SRR26342384/SRR26342384.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/007/SRR26342107/SRR26342107.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/059/SRR26342059/SRR26342059.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/093/SRR26342093/SRR26342093.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/078/SRR26341978/SRR26341978.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/090/SRR26341990/SRR26341990.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/093/SRR26342393/SRR26342393_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/045/SRR26342245/SRR26342245.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/041/SRR26342141/SRR26342141.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/023/SRR26342223/SRR26342223.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/072/SRR26342172/SRR26342172_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/077/SRR26342077/SRR26342077.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/046/SRR26342246/SRR26342246.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/068/SRR26342168/SRR26342168_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/099/SRR26341999/SRR26341999.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/008/SRR26341908/SRR26341908_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/099/SRR26342099/SRR26342099.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/010/SRR26342410/SRR26342410.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/077/SRR26341977/SRR26341977.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/098/SRR26342398/SRR26342398_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/040/SRR26342140/SRR26342140.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/023/SRR26342123/SRR26342123.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/041/SRR26342241/SRR26342241.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/001/SRR26342101/SRR26342101.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/024/SRR26342224/SRR26342224.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/063/SRR26342263/SRR26342263.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/085/SRR26342385/SRR26342385.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/099/SRR26342199/SRR26342199.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/098/SRR26342098/SRR26342098.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/089/SRR26342389/SRR26342389_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/063/SRR26342363/SRR26342363.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/076/SRR26342076/SRR26342076.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/002/SRR26342102/SRR26342102.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/040/SRR26342240/SRR26342240.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/024/SRR26342124/SRR26342124.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/062/SRR26342262/SRR26342262.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/008/SRR26342108/SRR26342108.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/079/SRR26341979/SRR26341979.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/096/SRR26341996/SRR26341996.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/020/SRR26342120/SRR26342120.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/001/SRR26342001/SRR26342001.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/012/SRR26341912/SRR26341912_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/094/SRR26342394/SRR26342394_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/044/SRR26342244/SRR26342244.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/070/SRR26342270/SRR26342270_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/061/SRR26342261/SRR26342261.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/003/SRR26342103/SRR26342103.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/004/SRR26342404/SRR26342404_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/097/SRR26342097/SRR26342097.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/042/SRR26342242/SRR26342242.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/078/SRR26342078/SRR26342078.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/049/SRR26342349/SRR26342349.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/092/SRR26342092/SRR26342092.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/027/SRR26342227/SRR26342227.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/080/SRR26342380/SRR26342380.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/083/SRR26342383/SRR26342383.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/002/SRR26341902/SRR26341902_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/071/SRR26342271/SRR26342271_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/068/SRR26342368/SRR26342368.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/081/SRR26342381/SRR26342381.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/029/SRR26342229/SRR26342229.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/094/SRR26342094/SRR26342094.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/022/SRR26342122/SRR26342122.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/005/SRR26342105/SRR26342105.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/006/SRR26342106/SRR26342106.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/094/SRR26341994/SRR26341994.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/082/SRR26342382/SRR26342382.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/095/SRR26342095/SRR26342095.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/021/SRR26342121/SRR26342121.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/003/SRR26341903/SRR26341903_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/095/SRR26341995/SRR26341995.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/009/SRR26341909/SRR26341909_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/028/SRR26342228/SRR26342228.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/079/SRR26342079/SRR26342079.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/066/SRR26342366/SRR26342366.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/006/SRR26342406/SRR26342406_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/012/SRR26342412/SRR26342412.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/013/SRR26342013/SRR26342013.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/082/SRR26342282/SRR26342282.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/048/SRR26342248/SRR26342248.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/030/SRR26342030/SRR26342030.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/065/SRR26342265/SRR26342265.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/089/SRR26341989/SRR26341989.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/019/SRR26341919/SRR26341919.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/012/SRR26342312/SRR26342312.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/065/SRR26342365/SRR26342365.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/053/SRR26341953/SRR26341953.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/048/SRR26342048/SRR26342048.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/048/SRR26342148/SRR26342148.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/082/SRR26342182/SRR26342182.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/011/SRR26341911/SRR26341911_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/068/SRR26342168/SRR26342168_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/012/SRR26342212/SRR26342212.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/030/SRR26342130/SRR26342130.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/047/SRR26342347/SRR26342347.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/071/SRR26341971/SRR26341971.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/054/SRR26341954/SRR26341954.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/064/SRR26342364/SRR26342364.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/082/SRR26342082/SRR26342082.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/083/SRR26342183/SRR26342183.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/003/SRR26341903/SRR26341903_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/031/SRR26342031/SRR26342031.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/011/SRR26342411/SRR26342411.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/070/SRR26341970/SRR26341970.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/048/SRR26342348/SRR26342348.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/083/SRR26342083/SRR26342083.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/047/SRR26342247/SRR26342247.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/099/SRR26342299/SRR26342299.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/066/SRR26342266/SRR26342266.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/083/SRR26342283/SRR26342283.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/012/SRR26342012/SRR26342012.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/011/SRR26342211/SRR26342211.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/067/SRR26342067/SRR26342067.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/046/SRR26342346/SRR26342346.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/014/SRR26342014/SRR26342014.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/047/SRR26342047/SRR26342047.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/081/SRR26342081/SRR26342081.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/031/SRR26342231/SRR26342231.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/049/SRR26342249/SRR26342249.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/064/SRR26342264/SRR26342264.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/013/SRR26342413/SRR26342413.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/080/SRR26342280/SRR26342280.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/066/SRR26342066/SRR26342066.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/049/SRR26342049/SRR26342049.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/030/SRR26342230/SRR26342230.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/020/SRR26341920/SRR26341920.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/065/SRR26342065/SRR26342065.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/013/SRR26342213/SRR26342213.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/096/SRR26342396/SRR26342396_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/072/SRR26341972/SRR26341972.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/014/SRR26342414/SRR26342414.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/081/SRR26342281/SRR26342281.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/014/SRR26342214/SRR26342214.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/064/SRR26342064/SRR26342064.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/004/SRR26341904/SRR26341904_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/003/SRR26342403/SRR26342403_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/029/SRR26342329/SRR26342329.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/063/SRR26342063/SRR26342063.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/046/SRR26342046/SRR26342046.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/010/SRR26341910/SRR26341910_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/010/SRR26342310/SRR26342310.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/098/SRR26342298/SRR26342298.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/028/SRR26342328/SRR26342328.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/005/SRR26341905/SRR26341905_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/032/SRR26342332/SRR26342332.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/029/SRR26342129/SRR26342129.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/063/SRR26342163/SRR26342163.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/085/SRR26342185/SRR26342185.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/067/SRR26342267/SRR26342267.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/033/SRR26342033/SRR26342033.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/056/SRR26341956/SRR26341956.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/034/SRR26341934/SRR26341934.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/029/SRR26342029/SRR26342029.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/067/SRR26342167/SRR26342167.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/084/SRR26342184/SRR26342184.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/085/SRR26342285/SRR26342285.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/062/SRR26342162/SRR26342162.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/045/SRR26342145/SRR26342145.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/068/SRR26342268/SRR26342268.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/055/SRR26341955/SRR26341955.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/000/SRR26342400/SRR26342400_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/015/SRR26342015/SRR26342015.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/012/SRR26341912/SRR26341912_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/033/SRR26341933/SRR26341933.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/032/SRR26342032/SRR26342032.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/046/SRR26342146/SRR26342146.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/084/SRR26342284/SRR26342284.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/039/SRR26341939/SRR26341939.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/010/SRR26342210/SRR26342210.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/017/SRR26341917/SRR26341917.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/016/SRR26342016/SRR26342016.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/011/SRR26342311/SRR26342311.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/047/SRR26342147/SRR26342147.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/052/SRR26341952/SRR26341952.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/035/SRR26341935/SRR26341935.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/034/SRR26342034/SRR26342034.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/081/SRR26342181/SRR26342181.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/064/SRR26342164/SRR26342164.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/045/SRR26342045/SRR26342045.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/017/SRR26342017/SRR26342017.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/018/SRR26341918/SRR26341918.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/028/SRR26342028/SRR26342028.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/009/SRR26341909/SRR26341909_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/002/SRR26342402/SRR26342402_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/089/SRR26342389/SRR26342389_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/051/SRR26342051/SRR26342051.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/038/SRR26341938/SRR26341938.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/086/SRR26342286/SRR26342286.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/097/SRR26342297/SRR26342297.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/095/SRR26342395/SRR26342395_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/016/SRR26342316/SRR26342316.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/031/SRR26342331/SRR26342331.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/014/SRR26342314/SRR26342314.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/096/SRR26342296/SRR26342296.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/037/SRR26341937/SRR26341937.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/079/SRR26342279/SRR26342279.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/013/SRR26342313/SRR26342313.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/030/SRR26342330/SRR26342330.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/049/SRR26342149/SRR26342149.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/066/SRR26342166/SRR26342166.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/094/SRR26342394/SRR26342394_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/015/SRR26342315/SRR26342315.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/080/SRR26342180/SRR26342180.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/050/SRR26341950/SRR26341950.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/036/SRR26341936/SRR26341936.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/065/SRR26342165/SRR26342165.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/027/SRR26342027/SRR26342027.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/050/SRR26342050/SRR26342050.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/051/SRR26341951/SRR26341951.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/078/SRR26342378/SRR26342378.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/018/SRR26342018/SRR26342018.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/087/SRR26342187/SRR26342187.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/017/SRR26342317/SRR26342317.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/034/SRR26342334/SRR26342334.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/051/SRR26342351/SRR26342351.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/099/SRR26341899/SRR26341899_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/078/SRR26342278/SRR26342278.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/052/SRR26342152/SRR26342152.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/067/SRR26341967/SRR26341967.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/005/SRR26341905/SRR26341905_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/018/SRR26342118/SRR26342118.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/034/SRR26342234/SRR26342234.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/098/SRR26342398/SRR26342398_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/044/SRR26342044/SRR26342044.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/032/SRR26341932/SRR26341932.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/017/SRR26342117/SRR26342117.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/070/SRR26342170/SRR26342170_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/031/SRR26341931/SRR26341931.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/083/SRR26341983/SRR26341983.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/018/SRR26342218/SRR26342218.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/060/SRR26342060/SRR26342060.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/077/SRR26342377/SRR26342377.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/091/SRR26342391/SRR26342391_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/061/SRR26342061/SRR26342061.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/017/SRR26342217/SRR26342217.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/018/SRR26342318/SRR26342318.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/033/SRR26342333/SRR26342333.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/084/SRR26341984/SRR26341984.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/068/SRR26341968/SRR26341968.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/036/SRR26342136/SRR26342136.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/019/SRR26342119/SRR26342119.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/050/SRR26342350/SRR26342350.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/000/SRR26342300/SRR26342300.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/086/SRR26342186/SRR26342186.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/053/SRR26342153/SRR26342153.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/001/SRR26341901/SRR26341901_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/016/SRR26341916/SRR26341916.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/062/SRR26342062/SRR26342062.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/007/SRR26341907/SRR26341907_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/035/SRR26342335/SRR26342335.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/001/SRR26342401/SRR26342401_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/016/SRR26342216/SRR26342216.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/030/SRR26341930/SRR26341930.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/049/SRR26341949/SRR26341949.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/096/SRR26342396/SRR26342396_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/079/SRR26342379/SRR26342379.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/036/SRR26342336/SRR26342336.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/009/SRR26342409/SRR26342409.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/053/SRR26342353/SRR26342353.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/015/SRR26341915/SRR26341915.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/065/SRR26341965/SRR26341965.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/082/SRR26341982/SRR26341982.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/034/SRR26342134/SRR26342134.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/050/SRR26342150/SRR26342150.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/066/SRR26341966/SRR26341966.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/051/SRR26342151/SRR26342151.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/088/SRR26342188/SRR26342188.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/035/SRR26342135/SRR26342135.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/008/SRR26342408/SRR26342408.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/013/SRR26341913/SRR26341913.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/014/SRR26341914/SRR26341914.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/052/SRR26342352/SRR26342352.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/007/SRR26342407/SRR26342407.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/006/SRR26342406/SRR26342406_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/090/SRR26342390/SRR26342390_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/032/SRR26342232/SRR26342232.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/054/SRR26342254/SRR26342254.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/015/SRR26342215/SRR26342215.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/080/SRR26342080/SRR26342080.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/037/SRR26342237/SRR26342237.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/074/SRR26342174/SRR26342174_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/015/SRR26342115/SRR26342115.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/054/SRR26342354/SRR26342354.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/011/SRR26342011/SRR26342011.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/076/SRR26342376/SRR26342376.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/086/SRR26341986/SRR26341986.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/089/SRR26342189/SRR26342189.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/085/SRR26342085/SRR26342085.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/011/SRR26342111/SRR26342111.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/070/SRR26342370/SRR26342370.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/010/SRR26342010/SRR26342010.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/033/SRR26342133/SRR26342133.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/016/SRR26342116/SRR26342116.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/071/SRR26342371/SRR26342371.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/001/SRR26342401/SRR26342401_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/084/SRR26342084/SRR26342084.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/032/SRR26342132/SRR26342132.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/010/SRR26342110/SRR26342110.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/097/SRR26342397/SRR26342397_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/095/SRR26342395/SRR26342395_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/069/SRR26341969/SRR26341969.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/068/SRR26342068/SRR26342068.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/085/SRR26341985/SRR26341985.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/000/SRR26341900/SRR26341900_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/031/SRR26342131/SRR26342131.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/069/SRR26342069/SRR26342069.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/033/SRR26342233/SRR26342233.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/086/SRR26342086/SRR26342086.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/050/SRR26342250/SRR26342250.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/014/SRR26342114/SRR26342114.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/057/SRR26342357/SRR26342357.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/053/SRR26342253/SRR26342253.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/089/SRR26342089/SRR26342089.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/038/SRR26342238/SRR26342238.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/072/SRR26342372/SRR26342372.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/019/SRR26342219/SRR26342219.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/006/SRR26341906/SRR26341906_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/088/SRR26341988/SRR26341988.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/075/SRR26342375/SRR26342375.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/088/SRR26342088/SRR26342088.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/087/SRR26341987/SRR26341987.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/012/SRR26342112/SRR26342112.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/058/SRR26342358/SRR26342358.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/052/SRR26342252/SRR26342252.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/035/SRR26342235/SRR26342235.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/036/SRR26342236/SRR26342236.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/074/SRR26342374/SRR26342374.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/087/SRR26342087/SRR26342087.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/059/SRR26342359/SRR26342359.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/051/SRR26342251/SRR26342251.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/002/SRR26342402/SRR26342402_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR263/013/SRR26342113/SRR26342113.fastq.gzprimaryOK200GenomicsDepartment of Systems Biology, Columbia Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA1026607Homo sapiensxref:PubMed:38061356Transcription factors have proven difficult to target with small molecule inhibitors because they often lack deep pockets necessary for potent binding. Alternatively, disruption of protein expression can suppress difficult targets and enable therapeutic intervention. To this end, we have developed a drug discovery workflow that incorporates cell line-selective screening and high-throughput expression profiling followed by regulatory network analysis to identify compounds that suppress regulatory drivers of disease. Applying this approach to neuroblastoma (NBL), we screened bioactive molecules in cell lines representing the MYC-dependent (MYCNA) and mesenchymal (MES) subtypes to identify selective compounds, followed by PLATESeq profiling of treated cells. This revealed compounds that disrupt a network of MYCNA-specific regulatory proteins, resulting in MYCN degradation in vivo. The top hit was isopomiferin, a prenylated isoflavonoid that inhibited Casein Kinase 2 (CK2) in cells. Isopomiferin and its structural analogs inhibited MYC and MYCN in NBL and lung cancer cells, highlighting the general MYC-inhibiting potential of this unique scaffold. Overall design: First Experiment (PLATESeq): To identify NBL MYCNA subtype-selective inhibitors, we systematically screened >5,000 compounds from three chemical libraries chosen for their enrichment of bioactive molecules, diversity in chemical structure, and for inclusion of compounds with known mechanisms of action. Compounds were initially tested at a single concentration and time-point (20 µM for 72 h) to eliminate those with no in vitro activity in NBL cell lines. Lethal compounds were rescreened across a five-point dilution series ranging from 20 µM to ~250 nM, to determine IC50 values in each of the four cell lines. By ranking compounds based on average IC50 values for each of the two subtypes, MYCNA or MES-selective compounds were identified. The top 90 compounds with the highest relative MYCNA-specific selectivity were then used to generate PLATESeq expression profiles following 24 hours of treatment in SK-N-Be2 cell lines at their respective IC20 concentration. Second Experiment (PLATESeq): top 15 compounds were screened with PLATESeq at 6 and 24 hours at multiple concentrations in three replicates Third Experiment (PLATESeq): In an effort to identify a potent analog of isopomiferin, we assembled a small collection of structurally-related analogs and known CK2 inhibitors, and tested them in SK-N-Be2 cells using PLATESeq TruSeq Experiment (RNASeq): To uncover kinase targets of isopomiferin and its functional analogs, we developed a novel algorithm, the Virtual-Inference of Kinase INhibiton by Gene regulatory networks (VIKING), to enable data-driven inference of drug targets based on activity dysregulation of protein-protein interactions (PPIs). VIKING was run using RNASeq (TruSeq) data on isopomiferin, pomiferin and its null analog, at multiple concentrations and timepoints.ENAfalseSubtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancersSubtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers2025-09-242023-10-12PRJNA1026607GSE245006960638061356