ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/025/SRR26453325/SRR26453325_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/037/SRR26453337/SRR26453337_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/013/SRR26453313/SRR26453313_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/014/SRR26453314/SRR26453314_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/027/SRR26453327/SRR26453327_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/015/SRR26453315/SRR26453315_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/030/SRR26453330/SRR26453330_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/024/SRR26453324/SRR26453324_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/031/SRR26453331/SRR26453331_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/030/SRR26453330/SRR26453330_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/036/SRR26453336/SRR26453336_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/028/SRR26453328/SRR26453328_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/025/SRR26453325/SRR26453325_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/016/SRR26453316/SRR26453316_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/013/SRR26453313/SRR26453313_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/012/SRR26453312/SRR26453312_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/009/SRR26453309/SRR26453309_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/031/SRR26453331/SRR26453331_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/020/SRR26453320/SRR26453320_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/019/SRR26453319/SRR26453319_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/008/SRR26453308/SRR26453308_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/034/SRR26453334/SRR26453334_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/028/SRR26453328/SRR26453328_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/023/SRR26453323/SRR26453323_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/022/SRR26453322/SRR26453322_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/017/SRR26453317/SRR26453317_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/016/SRR26453316/SRR26453316_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/011/SRR26453311/SRR26453311_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/010/SRR26453310/SRR26453310_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/035/SRR26453335/SRR26453335_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/029/SRR26453329/SRR26453329_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/026/SRR26453326/SRR26453326_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/032/SRR26453332/SRR26453332_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/033/SRR26453333/SRR26453333_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/017/SRR26453317/SRR26453317_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/021/SRR26453321/SRR26453321_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/018/SRR26453318/SRR26453318_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/020/SRR26453320/SRR26453320_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/029/SRR26453329/SRR26453329_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/032/SRR26453332/SRR26453332_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/018/SRR26453318/SRR26453318_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/034/SRR26453334/SRR26453334_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/019/SRR26453319/SRR26453319_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/022/SRR26453322/SRR26453322_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/015/SRR26453315/SRR26453315_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/010/SRR26453310/SRR26453310_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/027/SRR26453327/SRR26453327_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/035/SRR26453335/SRR26453335_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/012/SRR26453312/SRR26453312_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/037/SRR26453337/SRR26453337_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/033/SRR26453333/SRR26453333_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/036/SRR26453336/SRR26453336_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/011/SRR26453311/SRR26453311_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/021/SRR26453321/SRR26453321_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/014/SRR26453314/SRR26453314_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/023/SRR26453323/SRR26453323_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/024/SRR26453324/SRR26453324_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/026/SRR26453326/SRR26453326_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/009/SRR26453309/SRR26453309_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR264/008/SRR26453308/SRR26453308_1.fastq.gzprimaryOK200GenomicsKorean Institute of Oriental Medicinehttps://www.ebi.ac.uk/ena/browser/view/PRJNA1030369Homo sapiensThis study aimed to identify transcript expression induced by tonifying herbal medicines (THM) and modes of action (MOA) of THM in A549 cell line. For the production of THM-induced transcripts, tonifying herbal medicines water extract (THW) and tonifying herbal medicines ethanol extract (THE) were used. Overall design: Comparative gene expression profiling analysis of RNA-seq data for THW (500 ug/mL, 100 ug/mL, and 20 ug/mL, respectively), THE (500 ug/mL, 100 ug/mL, and 20 ug/mL, respectively), positive control (wortmannin, LY294002, and thioridazine 10uM, respectively), and vehicle control (2% DMSO). However, in extracts with IC20 of less than 500ug/mL, the concentration at IC20 and the concentration diluted to 1/5 and 1/25 of the IC20 concentration were used, respectively.ENAfalseDigital transformation of herbal medicine: Conversion to biological entity data using tonifying herbal medicine-induced transcriptome sequencing_SW1783_batchCDigital transformation of herbal medicine: Conversion to biological entity data using tonifying herbal medicine-induced transcriptome sequencing_SW1783_batchC2025-09-242024-06-23PRJNA1030369GSE2459039606