ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR277/066/SRR27717366/SRR27717366_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR277/065/SRR27717365/SRR27717365_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR277/064/SRR27717364/SRR27717364_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR277/063/SRR27717363/SRR27717363_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR277/065/SRR27717365/SRR27717365_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR277/064/SRR27717364/SRR27717364_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR277/066/SRR27717366/SRR27717366_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR277/063/SRR27717363/SRR27717363_1.fastq.gzprimaryOK200GenomicsKey Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, The First Hospital of Jilin University, Jilin University, Changchun, Chinahttps://www.ebi.ac.uk/ena/browser/view/PRJNA1068632Mus musculusTo further understand the downstream mechanism of IL17/IL17R signaling in tumor cells, we performed transcriptome sequencing analysis of 4T1 cells treated with rIL17A Overall design: KEGG analysis showing the top ten pathways predicted using genes changed significantly in LYVE-1+ TAMs between 4T1WT group and 4T1Opn-KO group. All genes were statistically changed (|log2(FC)|>1.2 & Pvalue <0.05).ENAfalseIL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [II]IL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [II]2025-09-242024-11-17PRJNA1068632GSE25414710090