{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/060/SRR27819660/SRR27819660_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/054/SRR27819654/SRR27819654_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/062/SRR27819662/SRR27819662_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/058/SRR27819658/SRR27819658_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/064/SRR27819664/SRR27819664_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/056/SRR27819656/SRR27819656_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/060/SRR27819660/SRR27819660_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/054/SRR27819654/SRR27819654_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/062/SRR27819662/SRR27819662_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/063/SRR27819663/SRR27819663_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/059/SRR27819659/SRR27819659_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/056/SRR27819656/SRR27819656_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/061/SRR27819661/SRR27819661_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/055/SRR27819655/SRR27819655_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/065/SRR27819665/SRR27819665_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/059/SRR27819659/SRR27819659_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/065/SRR27819665/SRR27819665_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/057/SRR27819657/SRR27819657_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/061/SRR27819661/SRR27819661_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/055/SRR27819655/SRR27819655_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/058/SRR27819658/SRR27819658_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/064/SRR27819664/SRR27819664_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/057/SRR27819657/SRR27819657_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR278/063/SRR27819663/SRR27819663_1.fastq.gz"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Nobile Lab, Molecular and Cell Biology, University of California MERCED"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA1071586"],"scientific_name":["Candida albicans"],"long_description":["The Hxk1 protein of Candida albicans is a moonlighting protein with a wide variety of functions. It phosphorylates N-acetylglucosamine (GlcNAc) which is necessary for different purposes in the cell including energy and chitin production. Further, this protein is a regulator for morphogenesis independent of its function during GlcNAc catabolism.To identify the regulatory role of Hxk1 and putative downstream regulator Hxk2, we performed CUT&RUN experiments for GFP-tagged Hxk1 strains and GFP-tagged Hxk2 strains. Overall design: CUT&RUN for 3 biological replicates of GFP-tagged Hxk1, GFP-tagged Hxk2 and corresponding IgG negative controls."],"tag":["pathogen:priority","pathogen","pathogen:fungus"],"repository":["ENA"],"classification":["fungi"],"additional_accession":[]},"is_claimable":false,"name":"The Hxk1 protein of Candida albicans influences gene expression of both metabolic and virulence related genes","description":"The Hxk1 protein of Candida albicans influences gene expression of both metabolic and virulence related genes","dates":{"last_updated":"2025-09-24","first_public":"2024-02-14"},"accession":"PRJNA1071586","cross_references":{"GEO":["GSE254730"],"taxon":["5476"]}}