ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/060/SRR28161960/SRR28161960_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/072/SRR28161972/SRR28161972_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/074/SRR28161974/SRR28161974_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/076/SRR28161976/SRR28161976_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/064/SRR28161964/SRR28161964_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/061/SRR28161961/SRR28161961_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/070/SRR28161970/SRR28161970_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/073/SRR28161973/SRR28161973_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/069/SRR28161969/SRR28161969_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/065/SRR28161965/SRR28161965_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/059/SRR28161959/SRR28161959_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/066/SRR28161966/SRR28161966_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/063/SRR28161963/SRR28161963_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/060/SRR28161960/SRR28161960_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/068/SRR28161968/SRR28161968_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/075/SRR28161975/SRR28161975_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/074/SRR28161974/SRR28161974_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/069/SRR28161969/SRR28161969_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/072/SRR28161972/SRR28161972_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/071/SRR28161971/SRR28161971_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/070/SRR28161970/SRR28161970_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/062/SRR28161962/SRR28161962_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/068/SRR28161968/SRR28161968_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/076/SRR28161976/SRR28161976_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/071/SRR28161971/SRR28161971_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/064/SRR28161964/SRR28161964_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/066/SRR28161966/SRR28161966_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/067/SRR28161967/SRR28161967_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/061/SRR28161961/SRR28161961_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/063/SRR28161963/SRR28161963_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/075/SRR28161975/SRR28161975_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/067/SRR28161967/SRR28161967_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/073/SRR28161973/SRR28161973_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/065/SRR28161965/SRR28161965_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/062/SRR28161962/SRR28161962_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR281/059/SRR28161959/SRR28161959_2.fastq.gzprimaryOK200Genomicsxinqiao hospitalhttps://www.ebi.ac.uk/ena/browser/view/PRJNA1082080mouse gut metagenomePrevious studies have shown that there is a close connection between constipation symptoms and gut flora disorders.In our study, knockdown of AQP8 could alleviate constipation in CKD mice by improving intestinal water-liquid transport and making feces soft and lubricated.Therefore, we investigated the effects of inhibiting AQP8 expression on the gut microbiota of CKD mice using 16S ribosomal RNA (rRNA) sequencing.ENAfalseMus musculus laetamenInhibition of AQP8 mitigates intestinal flora disruption in CKD mice2024-05-112024-05-11PRJNA1082080410661