{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Vaccines, Wyeth Research"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA108593"],"scientific_name":["Staphylococcus aureus"],"long_description":["MepR is a substrate-responsive repressor of mepR and mepA, which encode itself and a MATE family multidrug efflux pump. Microarray analyses of Staphylococcus aureus SH1000 and its mepR-disrupted derivative revealed changes in expression of many genes in addition to mepR and mepA, notably several involved in virulence Keywords: Staphylococcus aureus, MATE efflux pump, MepR Overall design: Staphylococcus aureus strains SH1000 wildtype and mepR were grown in duplicate to exponential and post-exponential phase (corresponding to an A550 nm of 0/4 and 2.0 respectively). RNA was harvested, converted to cDNA, labelled with Biotin and used to probe custom-designed Affymetrix antisense S.aureus GeneChips. Eight samples in total were prepared and analyzed."],"tag":["pathogen:priority","pathogen:bacterium","pathogen"],"classification":["bacteria"],"repository":["ENA"],"description_synonyms":["strain, Micrococcus pyogenes, Staphylococcus pyogenes aureus, Staphylococcus aureus subsp. anaerobius, Gene Expressions, Staphilococcus aureus, Sprain, Strain., Gene, cultivar, Expression, Staphylococus aureus, Strains, Micrococcus aureus, Sprains, Strains and Sprains, Expressions, Staphlococcus pyogenes citreus, ecotype, Streptococcus aureus"],"name_synonyms":["Staphylococus aureus, Micrococcus aureus, Micrococcus pyogenes, Staphylococcus pyogenes aureus, Staphylococcus aureus subsp. anaerobius, Streptococcus aureus., Staphlococcus pyogenes citreus, Staphilococcus aureus"],"additional_accession":[]},"is_claimable":false,"name":"Staphylococcus aureus","description":"Comparison of gene expression in Staphylococcus aureus strain SH1000 wildtype vs mepR","dates":{"last_updated":"2025-09-24","first_public":"2014-02-11"},"accession":"PRJNA108593","cross_references":{"GEO":["GSE10033"],"taxon":["1280"]}}