{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR286/029/SRR28621929/SRR28621929.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR286/031/SRR28621931/SRR28621931.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR286/030/SRR28621930/SRR28621930.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR286/028/SRR28621928/SRR28621928.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Skin lab, Clinical Insititute of immunology, Shanghai general hospital"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA1098861"],"scientific_name":["Mus musculus"],"long_description":["During the activation of CD4+T cells, the pri-miRNAs translocated from cytoplasma into nucleus.However, the mechanism remains unkown. We found that pri-miR-31 interact with nucleolin through G-guadruplex struction in pri-miR-31. We then transfected ASO to destribute the interaction of nucleolin and G4 struction. miRNA-seq was performed in our study. Overall design: ASO and its control CRO was transfected into naïve CD4+ T cells. The transfected cells were activated by anti-cd3/28. After 48 hours, cells were collected and went for RNA extraction. miRNA-seq was then ferformed."],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"miRNA-seq of CD4+ T cells transfected by ASO or CRO","description":"miRNA-seq of CD4+ T cells transfected by ASO or CRO","dates":{"last_updated":"2025-09-24","first_public":"2025-04-12"},"accession":"PRJNA1098861","cross_references":{"GEO":["GSE263730"],"taxon":["10090"]}}