ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/008/SRR28963108/SRR28963108_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/006/SRR28963106/SRR28963106_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/011/SRR28963111/SRR28963111_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/010/SRR28963110/SRR28963110_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/004/SRR28963104/SRR28963104_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/005/SRR28963105/SRR28963105_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/009/SRR28963109/SRR28963109_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/006/SRR28963106/SRR28963106_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/003/SRR28963103/SRR28963103_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/011/SRR28963111/SRR28963111_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/009/SRR28963109/SRR28963109_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/005/SRR28963105/SRR28963105_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/010/SRR28963110/SRR28963110_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/008/SRR28963108/SRR28963108_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/007/SRR28963107/SRR28963107_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/007/SRR28963107/SRR28963107_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/003/SRR28963103/SRR28963103_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR289/004/SRR28963104/SRR28963104_2.fastq.gzprimaryOK200GenomicsCentro de Biologia Molecular Severo Ochoa, Lab 327, Biology, UNIVERSIDAD AUTONOMA DE MADRIDhttps://www.ebi.ac.uk/ena/browser/view/PRJNA1109296Homo sapiensxref:PubMed:39033228To test whether the activity of PIM proteins promotes an aberrant activation of the molecular cascades that are essential for the leukemogenic effects mediated by JAK/STAT pathway mutations, we analyzed RNA-seq data from M07e cells expressing JAK3Q988P that were treated with PIM447 or left untreated. Overall design: Comparative gene expression profiling analysis of RNA-seq data for M07e cells expressing JAK3Q988P that were treated with PIM447 or left untreated. Three replicates were used for each sample.ENAfalseEffect of PIM447 treatment on gene expression of M07e cells transduced with JAK3 Q988PEffect of PIM447 treatment on gene expression of M07e cells transduced with JAK3 Q988P2025-09-242024-07-16PRJNA1109296GSE266986960639033228