{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["NIH"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA1117971"],"scientific_name":["Homo sapiens"],"long_description":["To explore whether surgical treatment for prostate cancer leads to long-term immune changes, we conducted a pilot study of n=11 prostate cancer patients treated with radical prostatectomy. We also included n=8 patients managed with active surveillance as a comparison group. We examined intra-individual changes in circulating immune cell subsets using serial blood samples collected pre- and approximately 6-months post-prostatectomy, and from matched time points for the patients managed on active surveillance. Immune cell subsets were deconvoluted using genome-wide methylation data. We observed no meaningful changes in circulating immune cell subsets in either patient group, suggesting that any surgery-induced immune changes to the circulating immune profile may not be long-lasting. The... (for more see dbGaP study page.)"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Methylation-based immune deconvolution in prostate cancer patients before and after radical prostatectomy","description":"Methylation-based immune deconvolution in prostate cancer patients before and after radical prostatectomy","dates":{"last_updated":"2025-09-24","first_public":"2025-04-28"},"accession":"PRJNA1117971","cross_references":{"taxon":["9606"]}}