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& Systems Biology, CHDI"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA1129435"],"scientific_name":["Mus musculus"],"long_description":["Cerebral cortex and striatum were isolated from 6-month old Msh6+/- and Msh6-/- mice crossed with the Q140 knock-in (KI) HD mice and their respective controls. Transcriptomic analysis (RNASeq) was performed on 6 genotypes: WT, Q140, Msh6+/-, Q140 X Msh6+/-, Msh6-/-, and Q140 X Msh6-/-, 8 replicates per genotype. Overall design: RNASeq analysis was performed on samples from the cerebral cortex and striatum tissues of 6 months old wild type, Q140, Msh6+/-, Q140 X Msh6+/-, Msh6-/-, and Q140 X Msh6-/- mice. N = 8 per group (4M/4F)"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptional profiling of cerebral cortex and striatum from a mouse model of Huntington's disease (Q140) crossed with Msh6 heterozygous and homozygous mice","description":"Transcriptional profiling of cerebral cortex and striatum from a mouse model of Huntington's disease (Q140) crossed with Msh6 heterozygous and homozygous mice","dates":{"last_updated":"2025-09-24","first_public":"2025-02-12"},"accession":"PRJNA1129435","cross_references":{"GEO":["GSE271022"],"taxon":["10090"]}}