ENAGenomicsShanghai Cancer Institutehttps://www.ebi.ac.uk/ena/browser/view/PRJNA1140362Mus musculusTo illustrate the effects of COPI on the tumor immune microenvironment, we performed single-cell RNA sequencing (scRNA-seq) analysis to interrogate phenotypic and functional alterations of immune cells in Myr-AKT/YAPS127A- driven iCCA with (NAV) or without NAV2729(MOCK,30mg/kg) treatment. Overall design: CD45+ population isolated from single cells pooled with six tumors per group were used for scRNA-seq.ENAfalseTargeting COP I elicits CD8+ T cell-mediated anti-tumor immunity in preclinical models of Intrahepatic Cholangiocarcinoma (scRNA-seq)Targeting COP I elicits CD8+ T cell-mediated anti-tumor immunity in preclinical models of Intrahepatic Cholangiocarcinoma (scRNA-seq)2025-09-242025-07-25PRJNA1140362GSE27316810090