<HashMap><database>ENA</database><file_versions><headers><Content-Type>application/xml</Content-Type></headers><body><files><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR300/044/SRR30011544/SRR30011544_2.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR300/044/SRR30011544/SRR30011544_1.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR300/045/SRR30011545/SRR30011545_2.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR300/045/SRR30011545/SRR30011545_1.fastq.gz</Fastqsanger.gz></files><type>primary</type></body><statusCodeValue>200</statusCodeValue><statusCode>OK</statusCode></file_versions><scores/><additional><omics_type>Genomics</omics_type><center_name>Tsinghua University</center_name><full_dataset_link>https://www.ebi.ac.uk/ena/browser/view/PRJNA1140863</full_dataset_link><scientific_name>Homo sapiens</scientific_name><long_description>We discovered that HnRNPF is significantly upregulated in breast cancer tissues and is closely associated with the cell proliferation signaling pathway. Overexpression of HnRNPF notably inhibits cell proliferation in MDA-MB-231 breast cancer cells. HnRNPF promotes the expression of the cell cycle inhibitor p21. Overall design: To explore the impact of HnRNPF on gene expression in MDA-MB-231 cells, we knocked down the expression of HnRNPF by siRNA and performed transcriptome analysis.</long_description><repository>ENA</repository></additional><is_claimable>false</is_claimable><name>The impact of HnRNPF knockdown on gene expression in MDA-MB-231 cell line</name><description>The impact of HnRNPF knockdown on gene expression in MDA-MB-231 cell line</description><dates><last_updated>2025-09-24</last_updated><first_public>2024-09-02</first_public></dates><accession>PRJNA1140863</accession><cross_references><GEO>GSE273248</GEO><taxon>9606</taxon></cross_references></HashMap>