ENAGenomicsWalter Reed Army Institute of Researchhttps://www.ebi.ac.uk/ena/browser/view/PRJNA1157877One hundred and thirty-three healthy adult human subjects recruited from two sites underwent an experimental model that simulate progressive central hypovolemia, lower body negative pressure (LBNP). The first cohort (n = 46) was recruited from U.S. Army Institute of Surgical Research in San Antonio, TX. The second cohort (n = 87) was recruited from the Human Physiology Laboratory at the Mayo Clinic in Rochester, MN. Blood samples were collected before and after the LBNP procedure for multi-omics processing. Bioinformatic analysis will be performed to identify molecular profiles associated with response and tolerance to simulated progressive blood loss.ENAfalseMulti-omics Molecular Responses Associated with Tolerance to Progressive Simulated Hemorrhage in Healthy Adult Humans2025-07-102025-07-10PRJNA1157877