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k/vol1/fastq/SRR307/024/SRR30724124/SRR30724124_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/033/SRR30724133/SRR30724133_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/032/SRR30724132/SRR30724132_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/046/SRR30724146/SRR30724146_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/037/SRR30724137/SRR30724137_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/020/SRR30724120/SRR30724120_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/018/SRR30724118/SRR30724118_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/034/SRR30724134/SRR30724134_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/048/SRR30724148/SRR30724148_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/049/SRR30724149/SRR30724149_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/045/SRR30724145/SRR30724145_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR307/051/SRR30724151/SRR30724151_1.fastq.gzprimary200OKGenomicsDepartment of Biosciences, University of Milanhttps://www.ebi.ac.uk/ena/browser/view/PRJNA1162825Homo sapiensWe genereted via genome editing 293T cell lines with the heterozygous and homozygous nucleotide substitution c.1424A>G in the PNPT1 gene (namely EK81 and EK81.8, respectively), causing the amino acidic variation p.E475G, and studied their transcriptomes before and after 6 hours of treatment with 1 µM staurosporine to induce apoptosis Overall design: Comparative RNA expression analysis of RNA-seq data for 293T cells and its derivatives EK81 and EK81.8ENAold-35, HEK293T, Human Embryonic Kidney 293T, DFNB70, Materials, Transcriptome, Genetic, 293-T, 1200003F12Rik, 293tsA1609neo, Transcriptome Profile, Profile, COXPD13, Expression Profiles, Gene Expression Profile, Gene, HEK 293 T, PNPase, OLD35, INSDC_feature:gene, Profiles, Cistrons, 293 T, Signatures, 293T, Mutations, Pnptl1, Hek 293T, whole transcriptome, Old35, Gene Expression, HEK-293T, Material, Expression Signature, Gene Expression Profiles, Transcriptome Profiles., Expression Signatures, Gene Expression Signatures, Transcriptomes, Genetic Materials, Cistron, PNPASE, Gene Expression Signature, Signature, Expression Profile, Genetic Material, HEK-293-T, RCB2202old-35, HEK293T, Human Embryonic Kidney 293T, DFNB70, Materials, Transcriptome, Genetic, 293-T, 1200003F12Rik, 293tsA1609neo, Transcriptome Profile, Profile, COXPD13, Expression Profiles, Gene Expression Profile, Gene, HEK 293 T, PNPase, OLD35, INSDC_feature:gene, Profiles, Cistrons, 293 T, Signatures, 293T, Mutations, Pnptl1, Hek 293T, whole transcriptome, Old35, Gene Expression, HEK-293T, Material, Expression Signature, Gene Expression Profiles, Transcriptome Profiles., Expression Signatures, Gene Expression Signatures, Transcriptomes, Genetic Materials, Cistron, PNPASE, Gene Expression Signature, Signature, Expression Profile, Genetic Material, HEK-293-T, RCB2202falseEffect of p.E475G mutation in the PNPT1 gene on 293T global transcriptomeEffect of p.E475G mutation in the PNPT1 gene on 293T global transcriptome2025-09-242024-10-09PRJNA1162825GSE2775689606