{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Medical Institute of Bioregulation, Kyushu university"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA118929"],"scientific_name":["Mus musculus"],"long_description":["The roles of histone demethylase KDM7 in gene expression were analyzed by gene expression profiling experiments with the mouse neuroblastoma cell line Neuro2A. Overall design: In order to examine the effect of KDM7 in gene expression, we generated stable KDM7 knockdown cell lines in the mouse neuroblastoma cell line Neuro2A. Total RNAs were extracted from 5 cell lines and analyzed for gene expression profiles using the Affymetrix platform. Cell lines: Parental cells: Neuro2A (N2A) empty vector: Neuro2A transfected with empty vector EGFP KD: Neuro2A transfected with vector for EGFP knock down KDM7 KD1: Neuro2A transfected with vector 1 for KDM7 knock down KDM7 KD2: Neuro2A transfected with vector 2 for KDM7 knock down"],"tag":["xref:PubMed:20194436"],"repository":["ENA"],"description_synonyms":["Histone H2b, Histone H2a, Methyl-CpG-binding protein MBD2, DMTase, Demethylase, Histone H5, Histone H4, Histone H7, H3(any), Histone H3., Histone H1(s), Histone H1, Histone, Histone H3.3"],"name_synonyms":["Mus musculus, Laboratory Mice., House, Mus, Laboratory, Swiss, Mus domesticus, mouse, Mus musculus domesticus, Swiss Mouse, mouse <Mus musculus>, Mouse, House Mice, Swiss Mice, house mouse, Mice, Laboratory Mouse, House Mouse, mice C57BL/6xCBA/CaJ hybrid, domesticus, Mus muscaris"],"additional_accession":[]},"is_claimable":false,"name":"Mus musculus","description":"KDM7 is a dual demethylase for histone H3 lysines 9 and 27 and functions in brain development","dates":{"last_updated":"2025-09-24","first_public":"2014-02-11"},"accession":"PRJNA118929","cross_references":{"GEO":["GSE17494"],"taxon":["10090"],"PubMed":["20194436"]}}