{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Research-Rosen, Steven - MC, City of Hope National Medical Center"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA1242291"],"scientific_name":["Homo sapiens"],"long_description":["We screened 270,000 compounds from an NCI library for the ability to dock with the non-ATP-binding site of p38γ using virtual screen. The resulting candidate compounds were for cytotoxicity assays to the Hut78 CTCL cell line and identified CSH18 as one of the most promising agents. Overall design: To show downstream pathway that CSH18-mediated targeting of p38γ, we first isolated RNA and subjected to microarray analysis of treated vs. control cells and observed upregulation of TNF alpha in several top hit after assesments of its downstream pathways."],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Olfactory Receptors as Tumor Suppressors in Cutaneous T-Cell Lymphoma via p38γ Pathway Modulation","description":"Olfactory Receptors as Tumor Suppressors in Cutaneous T-Cell Lymphoma via p38γ Pathway Modulation","dates":{"last_updated":"2025-09-24","first_public":"2025-04-26"},"accession":"PRJNA1242291","cross_references":{"GEO":["GSE292987"],"taxon":["9606"]}}