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micsDevelopmental Neurobiology, St. Jude Children's Research Hospitalhttps://www.ebi.ac.uk/ena/browser/view/PRJNA1243386Mus musculusWe performed snRNA-seq on dorsal striatum of young adult (postnatal day 64) Df(16)1/+ mice and wildtype littermates. Nuclei were isolated from frozen tissue as previously described (PMID 30371670), and libraries were prepared using the 10× Genomics Chromium Next GEM Single Cell Kit (v3.1). Overall design: Mice were heterozygotes or wildtype littermates from the Df(16)1 line and a mixture of males and females. Heterozygotes are hemizygous in a region homologous to the human 22q11.2 locus.ENAfalsesnRNA-seq analysis of dorsal striatum in a mouse model of 22q11 deletion syndromesnRNA-seq analysis of dorsal striatum in a mouse model of 22q11 deletion syndrome2025-09-242025-06-29PRJNA1243386GSE29322910090