{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Albert Einstein college of Medicine"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA1246567"],"long_description":["Mycobacterium tuberculosis (Mtb) uses a specialized secretion system, ESX-5, to export numerous proteins during infection. Here, we found that deleting ESX-5 from Mtb not only prevented secretion of many ESX-5 substrates but also impacted other ESX systems. The M.tb esx5 mutant had increased ESX-1 substrate secretion but reduced ESX-3 expression."],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"","description":"An ESX-5 full locus deletion in Mycobacterium tuberculosis alters mycomembrane composition and boosts ESX-1 substrate secretion","dates":{"last_updated":"2025-07-04","first_public":"2025-07-04"},"accession":"PRJNA1246567","cross_references":{}}