{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Novartis Institutes for Biomedical Research"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA127591"],"scientific_name":["Mus musculus"],"tag":["xref:PubMed:24600036"],"long_description":["Apilimod is a reported TLR pathway antagonist in clinical trial. To understand the mode of action of apilimod, we applied global microarray analysis to explore the effect of apilimod on gene expression of RAW cell in the absence of presence of R848 (TLR7 ligand). Overall design: RAW cells were stimulated with R848 in the absence or presence of apilimod (1μM). mRNAs were extracted at 0h, 1h,3h, 7h, and 22h for affymetrix analysis. The inactive analog of apilimod (API09) was included as a control."],"repository":["ENA"],"description_synonyms":["Svc, number, Bru, count in organism, Del(8)44H, absence, Col4a-1, Raw, Cell, absent from organism, presence."],"name_synonyms":["Mus musculus, Laboratory Mice., House, Mus, Laboratory, Swiss, Mus domesticus, mouse, Mus musculus domesticus, Swiss Mouse, mouse <Mus musculus>, Mouse, House Mice, Swiss Mice, house mouse, Mice, Laboratory Mouse, House Mouse, mice C57BL/6xCBA/CaJ hybrid, domesticus, Mus muscaris"],"additional_accession":[]},"is_claimable":false,"name":"Mus musculus","description":"Microarry datasets for RAW cells stimulated with R848 in the absence or presence of apilimod or API09","dates":{"last_updated":"2025-09-24","first_public":"2014-02-20"},"accession":"PRJNA127591","cross_references":{"GEO":["GSE22124"],"taxon":["10090"],"PubMed":["24600036"]}}