{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Cellular Therapy of Diabetes, Regeneration and Cell Therapy, CABIMER"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA140283"],"scientific_name":["Mus musculus"],"long_description":["Lineage commitment during Embryonic Stem Cells (ESCs) differentiation is controlled not only by a gamut of transcription factors but also by epigenetic events, mainly histone deacetylation and promoter DNA methylation. Moreover, the DNA demethylation agent 5′-Aza-2′-deoxycytidine (AzadC) has been widely described in the literature as an effective chemical stimulus used to promote cardiomyogenic differentiation in various stem cell types however, its toxicity and instability complicate its use. Thus, the purpose of this study was to examine the effects of zebularine, a stable and non-toxic DNA cytosine methylation inhibitor, on ESCs differentiation. Herein are the Affymetrix Expression data obtained from RNA of murine ESCs treated with zebularine. Overall design: 9 control samples (replicates) and 9 zebularine samples (replicates)."],"tag":["xref:PubMed:23559004"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Mus musculus","description":"Zebularine effect on mouse embryonic stem cells manifested as cardiod-myogenic potential: testable hypothesis generation using microarray data","dates":{"last_updated":"2025-09-24","first_public":"2014-02-11"},"accession":"PRJNA140283","cross_references":{"GEO":["GSE29072"],"taxon":["10090"],"PubMed":["23559004"]}}