{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Singapore Immunology Network"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA162417"],"scientific_name":["Homo sapiens"],"long_description":["We used genetic approaches to identify butyrophilin 3A1 (BTN3A1) as the molecule that binds and presents phosphorylated antigens to Vγ9Vδ2 TCR–expressing cells. BTN3A1 represents a novel antigen–presenting molecule for the activation of Vγ9Vδ2 TCR–expressing cells which play important roles in human tumor immunity and host defense. Overall design: 3 replicates of 4 cell lines (12 samples total) were analysed. Data was RMA normalized, and genes that expressed above the negative control in all 4 cell lines from chromosome 6 considered for further analysis"],"repository":["ENA"],"description_synonyms":["Butyrophilin, Human, TCR, Responder protein Smok-Tcr, Tcr, 2.7.11.1, human being, Man (Taxonomy), TCR complex, Homo sapiens, T-lymphocyte receptor complex, Modern Man, Modern, Antigen, Dominant negative form of Smok, Cell., T-cell receptor complex, man, Man, human, T lymphocyte receptor complex, SmokTcr"],"name_synonyms":["Human, Modern., human being, Man (Taxonomy), Homo sapiens, man, Man, human, Modern Man"],"additional_accession":[]},"is_claimable":false,"name":"Homo sapiens","description":"Butyrophilin 3A1 binds phosphorylated antigens and stimulates human TCR γδ cells.","dates":{"last_updated":"2025-09-24","first_public":"2014-02-11"},"accession":"PRJNA162417","cross_references":{"GEO":["GSE37634"],"taxon":["9606"]}}