ENAGenomicsSingapore Immunology Networkhttps://www.ebi.ac.uk/ena/browser/view/PRJNA162417Homo sapiensWe used genetic approaches to identify butyrophilin 3A1 (BTN3A1) as the molecule that binds and presents phosphorylated antigens to Vγ9Vδ2 TCR–expressing cells. BTN3A1 represents a novel antigen–presenting molecule for the activation of Vγ9Vδ2 TCR–expressing cells which play important roles in human tumor immunity and host defense. Overall design: 3 replicates of 4 cell lines (12 samples total) were analysed. Data was RMA normalized, and genes that expressed above the negative control in all 4 cell lines from chromosome 6 considered for further analysisENAButyrophilin, Human, TCR, Responder protein Smok-Tcr, Tcr, 2.7.11.1, human being, Man (Taxonomy), TCR complex, Homo sapiens, T-lymphocyte receptor complex, Modern Man, Modern, Antigen, Dominant negative form of Smok, Cell., T-cell receptor complex, man, Man, human, T lymphocyte receptor complex, SmokTcrHuman, Modern., human being, Man (Taxonomy), Homo sapiens, man, Man, human, Modern ManfalseHomo sapiensButyrophilin 3A1 binds phosphorylated antigens and stimulates human TCR γδ cells.2025-09-242014-02-11PRJNA162417GSE376349606