ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530662/SRR530662.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530659/SRR530659.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530660/SRR530660.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530658/SRR530658.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530656/SRR530656.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530653/SRR530653.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530661/SRR530661.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530654/SRR530654.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530655/SRR530655.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR530/SRR530663/SRR530663.fastq.gzprimaryOK200GenomicsLaboratory of Computational Biology, Center for Human Genetics, KULeuvenhttps://www.ebi.ac.uk/ena/browser/view/PRJNA171883xref:PubMed:23070853In this study we use Tag-sequencing in eye-antennal and wing imaginal discs across Drosophila species to determine a set of conserved eye-specific developmental genes. Next, we perform motif discovery analysis using the tool i-cisTarget, to depict the core gene developmental network underlying compound eye photoreceptor. The Glass position weight matrix appears as the most highly overrepresented motif, thus positioning Glass as a master regulator in compound eye photoreceptor development. Differential gene expression analysis by RNA-seq in D.melanogaster wild-type eye-antennal versus glass mutant [gl 60j] shows that the majority of our predicted Glass targets show strong downregulation in the glass mutant. This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series.ENAfalseTag-seq in eye-antennal and wing imaginal discs of D.melanogaster, D.yakuba, and D.virilis RNA-seq in wild-type and glass mutant D.melanogaster eye-antennal imaginal discs.2025-09-242013-05-31PRJNA171883GSE3978423070853