ENAGenomicsMultiomicsoncovirology and Biotherapies, UMR5239, LBMChttps://www.ebi.ac.uk/ena/browser/view/PRJNA200718Homo sapiensT-cell clones were obtained by limiting dilution culture of PBMC of HTLV-1 carriers. Exon expression profiling was performed using Affymetrix exon array (Affymetrix Human Exon 1.0 ST Array) according to the manufacturer's instructions. Overall design: The main objectives were to assess whether transcriptional and post-transcriptional modifications associate with HTLV-1 infection in vivo. To this end, T-cell clones, infected or not by HTLV-1, were obtained by limiting dilution culture of PBMC derived from HTLV-1 carriers. Exon expression profiles of cloned T cells was analyzed using Affymetrix exon array (Affymetrix Human Exon 1.0 ST Array) according to the manufacturer's instructions.xref:PubMed:25205102ENAThymus-Dependent Lymphocytes, T-Cell Leukemia Virus I, T-cell surface antigen T4/Leu-3, determination, T-cell surface antigen T4|Leu-3, T-Lymphocyte, HTLV-1, Cell, Human, L3T4, Human T lymphotropic virus type 1, T Lymphocyte, T-cell differentiation antigen L3T4, T-Cell, Human T-Cell Leukemia Virus I, chemical analysis, Ly-4, Human T Cell, immature T cell, Adult T Cell Leukemia Lymphoma Virus I., T lymphocyte, Human T lymphotropic virus 1, T-cell, Adult T-Cell Leukemia-Lymphoma Virus I, T-Cells, T-cell surface glycoprotein CD4, Thymus-Dependent, T, T Cell Leukemia Virus I, CD4mut, Lymphocytes, Human T Cell Leukemia Virus I, T-lymphocyte, Thymus-Dependent Lymphocyte, T Cells, ATLV, T cell, Human T-Cell, mature T cell, Cells, CD4, HTLV-I, T Cell, assay, T Lymphocytes, Thymus Dependent Lymphocytes, Leukemia Lymphoma Virus I, Lymphocyte, Adult T Cell, Leukemia Virus IHuman, Modern., human being, Man (Taxonomy), Homo sapiens, man, Man, human, Modern ManfalseHomo sapiensTranscriptional and post-transcriptional analysis of CD4+ T cell clones deriving from HTLV-1 infected individuals2025-09-242014-12-05PRJNA200718GSE46518960625205102