{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Gene Regulation & Epigenetics, Institute of Experimental Genetics, Helmholtz Zentrum München GmbH"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA214789"],"scientific_name":["Mus musculus"],"long_description":["Cytochrome c oxidase (COX) is a 13-subunit enzyme that is a key complex of the oxidative phosphorylation system of the mitochondria, which generates the vast majority of the energy of the cell.COX subunit IV is the largest nuclear-encode subunit with important regulatory functions concerning energy metabolism. COX4-2 has been knocked out. Our study indicated strong expression of Cox4-2 in lung and therefore we test this mutant line under OVA-challenge conditions expecting a new asthma mouse model. Overall design: Total RNA obtained from 1/2 lung of 4 female mice of each analysed group (widltype, wildtype challenged, mutant, mutant challenged)"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Mus musculus","description":"Transcriptome analysis of Cox4-2 knockout mice after OVA challenge","dates":{"last_updated":"2025-09-24","first_public":"2015-07-18"},"accession":"PRJNA214789","cross_references":{"GEO":["GSE49694"],"taxon":["10090"]}}