ENAGenomicsGene Regulation & Epigenetics, Institute of Experimental Genetics, Helmholtz Zentrum München GmbHhttps://www.ebi.ac.uk/ena/browser/view/PRJNA214789Mus musculusCytochrome c oxidase (COX) is a 13-subunit enzyme that is a key complex of the oxidative phosphorylation system of the mitochondria, which generates the vast majority of the energy of the cell.COX subunit IV is the largest nuclear-encode subunit with important regulatory functions concerning energy metabolism. COX4-2 has been knocked out. Our study indicated strong expression of Cox4-2 in lung and therefore we test this mutant line under OVA-challenge conditions expecting a new asthma mouse model. Overall design: Total RNA obtained from 1/2 lung of 4 female mice of each analysed group (widltype, wildtype challenged, mutant, mutant challenged)ENAfalseMus musculusTranscriptome analysis of Cox4-2 knockout mice after OVA challenge2025-09-242015-07-18PRJNA214789GSE4969410090