ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR106/000/SRR1068420/SRR1068420.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR106/009/SRR1068419/SRR1068419.fastq.gzprimary200OKGenomicsDr. Xiaochun Yu, Internal Medicine, city of hopehttps://www.ebi.ac.uk/ena/browser/view/PRJNA233405Homo sapiensPGC7 is a primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. TET3 is a dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming in the zygote following fertilization. Overall design: PGC7 participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC by TET3 oxidization subsequent DNA demethylation. Thus we tested the co-localization of PGC7 and TET3 in specific loci by ChIP-seq assays.ENAHuman, Modern., human being, Man (Taxonomy), Homo sapiens, man, Man, human, Modern ManHITS-CLIP, High Throughput Sequencing of RNA Isolated by Crosslinking Immunoprecipitation, Chromatin Immunoprecipitation Sequencing Chip, results., ChIP-Chip, Chromatin Immuno precipitation Sequencing, B430006D22Rik, Chromatin Immuno-precipitation, ChIP, Chromatin Immunoprecipitation Paired End Tag, Cross Linking and Immunoprecipitation Followed by Deep Sequencing, Chromatin Immuno Precipitation Paired End Tag, Cross-Linking and Immunoprecipitation Followed by Deep Sequencing, ChIP Sequencing, Chromatin Immunoprecipitation, CLIP-Seq, Chromatin Immuno-precipitation Sequencing, Assay for Transposase-Accessible Chromatin Using Sequencing, ChIP Exonuclease, ChIP-PET, ChIP-Seq, Sequencing, ChIP-Exo, Assay for Transposase Accessible Chromatin Using Sequencing, BC037432, Chromatin Immunoprecipitation Paired-End Tag, 2410075G02Rik, PCG7, Stella, Chromatin Immuno-Precipitation Paired-End Tag, PGC7, ATAC-Seq, Chromatin Immunoprecipitation Sequencing-Chips, Chromatin Immunoprecipitation Sequencing-Chip, tetraspanin3, High-Throughput Sequencing of RNA Isolated by Crosslinking Immunoprecipitation, D230004J03Rik, ChIP-Exonuclease, ChIA-PETfalseHomo sapiensPGC7 and TET3 ChIP-seq results2025-09-242014-01-05PRJNA233405GSE538099606