ENAGenomicsMultiomicsZJUhttps://www.ebi.ac.uk/ena/browser/view/PRJNA233663Penaeus japonicusxref:PubMed:24352447In this study, the viral miRNAs from white spot syndrome virus (WSSV) were characterized in shrimp in vivo. On the basis of our previous study and small RNA sequencing in this study, a total of 89 putative WSSV miRNAs were identified. As revealed by miRNA microarray analysis, the expressions of viral miRNAs were tissue-specific in vivo. Overall design: In this study, the viral miRNAs from white spot syndrome virus (WSSV) were characterized in shrimp in vivo. On the basis of our previous study and small RNA sequencing in this study, a total of 89 putative WSSV miRNAs were identified. As revealed by miRNA microarray analysis and Northern blots, the expressions of viral miRNAs were tissue-specific in vivo. Therefore, our study presented the first report on the in vivo molecular events of viral miRNA in the antiviral apoptosis.ENAPenaeus (Melicertus) japonicus, Marsupenaeus japonicus, Penaeus (Marsupenaeus) japonicus.anti-viral agents, Regulations, antivirals, cellular suicide, RNA, antiviral agents, cell suicide, Caspase-Dependent Apoptosis, Formal Social Control, stRNA, caspase-dependent programmed cell death, apoptotic cell death, Small Temporal RNA, Caspase Dependent Apoptosis, Primary, Antiviral Drugs, anti-viral agent, Antiviral, Antiviral Agent, type I programmed cell death, apoptotic programmed cell death, activation of apoptosis, Social Controls, Antiviral Drug, Agent, Small, Micro RNA, signaling (initiator) caspase activity, induction of apoptosis, Extrinsic Pathway Apoptoses, Social Control, Intrinsic Pathway, Programmed, Programmed Cell Death, Extrinsic Pathway Apoptosis, antiviral, Type I, Caspase-Dependent, pre-miRNA, Formal Social Controls, pri miRNA, Drugs, apoptosis signaling, miRNAs, Small Temporal, programmed cell death by apoptosis., apoptosis, Micro, Temporal RNA, Control, Primary MicroRNA, Cell Death, miRNA, Primary miRNA, Controls, apoptosis activator activity, INSDC_feature:ncRNA, pri-miRNA, Social, Drug, Classic Apoptoses, Intrinsic Pathway Apoptoses, Intrinsic Pathway Apoptosis, Agents, induction of apoptosis by p53, Classic, Classic Apoptosis, apoptotic program, execution phase of apoptotic process, Classical Apoptosis, Extrinsic Pathway, commitment to apoptosis, MicroRNA, regulation, Antivirals, Regulation, Classical, pre miRNA, Apoptoses, ApoptosisfalsePenaeus japonicusInvolvement of viral miRNA in the regulation of antiviral apoptosis in shrimp2025-09-242014-02-11PRJNA233663GSE539002740524352447