ENAGenomicsHuang, Ob/Gyn, The Ohio State Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA240877Homo sapiensxref:PubMed:25847994Analysis of long-acting progestin-only contraceptive (LAPC)-mediated differential gene expression in vascular smooth muscle cells (VSMCs). We tested the hypothesis that LAPCs influence expression of several common genes associated with differentiation, survival and migration of VMSCs. Results provide important information of several common and unique gene expression profiles in cultured VSMC treated with ETO, M or P. Among ETO and M responsive genes, up- or down-regulated common genes were determined and used further confirmation and in vitro functional analyses. Overall design: Total RNA (n=3) obtained from cultured aortic VSMCs treated with vehicle only (CON) or ETO or M or P for 6h.ENA2-Epoxyaethan, Pregnenedione, determination, Vascular Smooth, ZMYND2, Progesteron, CDR, broad, 6 alpha Methyl 17alpha hydroxyprogesterone Acetate, vascular smooth muscle, Depo-Provera, 18, (6alpha)-, (6 alpha, Gelbkoerperhormon, 13-ethyl-17-hydroxy-11-methylene-18, Vascular, 3-keto-desogestrel, smooth muscle of blood vessel, 1, Depo-Medroxyprogesterone Acetate, Smooth Muscles, 19-dinorpregn-4-en-20-yn-3-one, Crinone, (S)-4-Pregnene-3, 17-(acetyloxy)-6-methyl-, 10 alpha)-Isomer, Curretab, Cycrin, Agolutin, Depo Provera, Genomes, Smooth Muscle, smooth muscle tissue of blood vessel, blood vessel smooth muscle tissue, epoxyethane, Vascular Smooth Muscle, Dimethylene oxide, Cbfa2t1h, Farlutal, 3-ketodesogestrel, (S)-Pregn-4-en-3, Gestapuran, Muscles, (S)-Progesterone, (17-alpha)-, Implanon, ethene oxide, Veramix, blood vessel non-striated muscle, Amprolene, ETO, (6 alpha)-17-(Acetoxy)-6-methylpregn-4-ene-3, Anprolene, 19-dinor-17alpha-pregn-4-en-20-yn-3-one, Oxacyclopropane, Anproline, wide/broad, 17 alpha)-Isomer, 17alpha-progesterone, Muscle, MTG8, Oxyfume, ORG-3236, corpus luteum hormone, Depo Medroxyprogesterone Acetate, Pregn-4-ene-3, involuntary muscle of blood vessel, Oxidoethane, chemical analysis, CBFA2T1, (9 beta, Dihydrooxirene, (6 beta)-Isomer, Oxane, nexplanon, 3-oxodesogestrel, Medroxyprogesterone 17 Acetate, 17 alpha)-(+-)-Isomer, luteohormone, Perlutex, (13 alpha, Akrolutin., non-striated muscle of blood vessel, 2-epoxyethane, 20-dione, DepoProvera, whole genome, 13-ethyl-17-hydroxy-11-methylene-, (17 alpha)-Isomer, Vascular Smooth Muscles, oxyde d'ethylene, Medroxyprogesterone 17-Acetate, wide, AML1T1, Provera, blood vessel involuntary muscle, 3-oxo desogestrel, vascular smooth muscle tissue, Aethylenoxid, Delta(4)-pregnene-3, assay, 4-Pregnene-3, Ethylene oxide, Progesterone, 6-alpha-Methyl-17alpha-hydroxyprogesterone AcetateHuman, Modern., human being, Man (Taxonomy), Homo sapiens, man, Man, human, Modern ManfalseHomo sapiensGenome-wide analysis of vascular smooth muscle cells treated by etonogestrel (ETO), medroxyprogesterone acetate (M) or progesterone (P)2025-09-242014-03-12PRJNA240877GSE55736960625847994