ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/004/SRR1216944/SRR1216944.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/001/SRR1216951/SRR1216951.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/006/SRR1216946/SRR1216946.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/009/SRR1216949/SRR1216949.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/005/SRR1216945/SRR1216945.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/002/SRR1216952/SRR1216952.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/003/SRR1216953/SRR1216953.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/002/SRR1216942/SRR1216942.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/003/SRR1216943/SRR1216943.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/008/SRR1216948/SRR1216948.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/000/SRR1216950/SRR1216950.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR121/007/SRR1216947/SRR1216947.fastq.gzprimaryOK200GenomicsNucleomics Core, VIBhttps://www.ebi.ac.uk/ena/browser/view/PRJNA243560Mus musculusThe transcriptome of pancreatic islets from four mouse strains was compared - NODk.RagKO, B10k.RagKO, NODk.RagKO.insHEL and B10k.RagKO.insHEL. This comparison allows the assessment of altered transcriptome due to two factors - genetic background of NOD vs B10 strain, and the effect of the insHEL transgene. The use of the MHC k haplotype and the RagKO background remove contamination from infiltrating immune cells, in order to obtain a pure islet transcriptome. Overall design: Three mice of each gentoype were analyzed in this study.ENAfalseMus musculusComparative assessment of the transcriptome of pancreatic islets from Non-Obese Diabetic mice in the absence of immune infiltrate2025-09-242016-10-10PRJNA243560GSE5650710090