ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/006/SRR1274586/SRR1274586.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/009/SRR1274599/SRR1274599.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/002/SRR1274622/SRR1274622.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/009/SRR1274629/SRR1274629.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/003/SRR1274603/SRR1274603.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/002/SRR1274592/SRR1274592.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/006/SRR1274616/SRR1274616.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/001/SRR1274591/SRR1274591.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/008/SRR1274598/SRR1274598.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/001/SRR1274621/SRR1274621.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/005/SRR1274615/SRR1274615.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/005/SRR1274585/SRR1274585.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/008/SRR1274628/SRR1274628.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/009/SRR1274609/SRR1274609.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/001/SRR1274611/SRR1274611.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/000/SRR1274590/SRR1274590.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/008/SRR1274588/SRR1274588.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/008/SRR1274618/SRR1274618.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/002/SRR1274602/SRR1274602.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/007/SRR1274597/SRR1274597.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/000/SRR1274630/SRR1274630.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/007/SRR1274627/SRR1274627.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/007/SRR1274587/SRR1274587.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/000/SRR1274610/SRR1274610.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/008/SRR1274608/SRR1274608.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/007/SRR1274617/SRR1274617.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/001/SRR1274601/SRR1274601.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/000/SRR1274620/SRR1274620.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/006/SRR1274596/SRR1274596.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/007/SRR1274607/SRR1274607.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/003/SRR1274613/SRR1274613.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/006/SRR1274626/SRR1274626.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/005/SRR1274595/SRR1274595.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/000/SRR1274600/SRR1274600.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/009/SRR1274589/SRR1274589.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/005/SRR1274625/SRR1274625.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/009/SRR1274619/SRR1274619.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/006/SRR1274606/SRR1274606.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/002/SRR1274582/SRR1274582.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/002/SRR1274612/SRR1274612.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/004/SRR1274624/SRR1274624.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/004/SRR1274594/SRR1274594.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/005/SRR1274605/SRR1274605.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/004/SRR1274584/SRR1274584.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/003/SRR1274593/SRR1274593.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/004/SRR1274614/SRR1274614.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/003/SRR1274583/SRR1274583.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/004/SRR1274604/SRR1274604.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR127/003/SRR1274623/SRR1274623.fastq.gzprimaryOK200GenomicsMultiomicsInserm U866https://www.ebi.ac.uk/ena/browser/view/PRJNA246388Mus musculusTo determine whether an accelerated aging-like phenotype occurs in hematopoiesis of young Tif1γ-/- mice (4 months old), we purified 200,000 hematopoietic stem cells (LSK: Lineage negative, Sca1+, c-Kit+) from Tif1γ-/- mice and performed high-throughput mRNA sequencing (RNA-seq). We compared this transcriptome to physiological aging by creating two other RNAseq libraries from young (4 months old) and old (20 months old) wild type mice. Overall design: RNAseq study on young Tif1γ-/- mice (4 months old), young wild type mice (4 months old) and old wild type mice (20 months old).xref:PubMed:25002492ENAfalseMus musculusAn aging-like phenotype occurs in Tif1γ-/- hematopoietic stem cells2025-09-242014-06-18PRJNA246388GSE573961009025002492