ENAGenomicsBiology and Biotechnology "C. Darwin", Sapienza University of Romehttps://www.ebi.ac.uk/ena/browser/view/PRJNA253317Homo sapiensxref:PubMed:25252716To investigate the effect of CEBPA on the expression of mRNAs and long non-coding RNAs ( lncRNAs), we utilized the K562 AML cell line carrying a stable and Tet-on inducible CEBPA allele. K562 cells lack endogenous CEBPA and restoration of its expression induces proliferation arrest and granulocytic differentiation . Overall design: Based on the expression of known CEBPA transcriptional targets, we selected RNA extracted from 48 hours of induction (CEBPA) together with RNA extracted from control-induced cells (CTR). 4 biological replicates for each sample have been utilized.ENAfalseHomo sapiensIdentification of transcripts regulated by CEBPA in K5622025-09-242014-09-01PRJNA253317GSE58743960625252716