{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Sun-Yat-Sen Memorial Hospital"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA255113"],"scientific_name":["Homo sapiens"],"tag":["xref:PubMed:26436920"],"long_description":["To examine the miRNA expression profile of the profibrogenic macrophages, we compared miRNA expression in untreated versus IL-4 or IL-13-treated macrophages using miRNA microarray.IL-4 and IL-13 treatment resulted in marked changes in 18 and 19 miRNAs in macrophages, respectively.(n=3, fold changes>2, P<0.05) Overall design: Total RNA from human primary macrophages (n=3) treated with or without 20 ng/ml IL-4 or 20ng/ml IL-13 for 48 hr was isolated with a mirVana miRNA Isolation kit (Ambion, Foster, CA). The miRNA expression profile of the samples were examined using miRCURY LNA™ arrays (v18.0 covering 1921 human miRNAs, Exiqon ,Vedbaek, Denmark)."],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Homo sapiens","description":"M2 cytokines alter the miRNA expression profile in macrophages","dates":{"last_updated":"2025-09-24","first_public":"2014-07-13"},"accession":"PRJNA255113","cross_references":{"GEO":["GSE59348"],"taxon":["9606"],"PubMed":["26436920"]}}