{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Tokyo Metropolitan Institute of Gerontology"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA275742"],"scientific_name":["Homo sapiens"],"long_description":["Prostate cancer is the most common cancer in men. We identified that miR-29 family is the most androgen-responsive miRNA in hormone-refractory prostate cancer cells. For the screening of miR-29b target, we performed microarray analysis in two prostate cancer cells. Because TET2 is the primary target of miR-29 family by our analysis, we also performed TET2 signaling by microarray. In order to investigate the downsteam signals mediated by TET2 and miR-29b, we performed comprehensive analysis of gene expression in positive prostate cancer cell lines after siTET2 or miR-29b treatment. Overall design: Observation of gene expression changes after treatmet with siRNA targeting TET2 or miR-29b in prostate cancer cell lines with microarray."],"tag":["xref:PubMed:26404510"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Homo sapiens","description":"Effects of miRNA-mediated TET2 in prostate cancer","dates":{"last_updated":"2025-09-24","first_public":"2015-09-01"},"accession":"PRJNA275742","cross_references":{"GEO":["GSE66038"],"taxon":["9606"],"PubMed":["26404510"]}}