<HashMap><database>ENA</database><scores/><additional><omics_type>Genomics</omics_type><center_name>Tokyo Metropolitan Institute of Gerontology</center_name><full_dataset_link>https://www.ebi.ac.uk/ena/browser/view/PRJNA275742</full_dataset_link><scientific_name>Homo sapiens</scientific_name><long_description>Prostate cancer is the most common cancer in men. We identified that miR-29 family is the most androgen-responsive miRNA in hormone-refractory prostate cancer cells. For the screening of miR-29b target, we performed microarray analysis in two prostate cancer cells. Because TET2 is the primary target of miR-29 family by our analysis, we also performed TET2 signaling by microarray. In order to investigate the downsteam signals mediated by TET2 and miR-29b, we performed comprehensive analysis of gene expression in positive prostate cancer cell lines after siTET2 or miR-29b treatment. Overall design: Observation of gene expression changes after treatmet with siRNA targeting TET2 or miR-29b in prostate cancer cell lines with microarray.</long_description><tag>xref:PubMed:26404510</tag><repository>ENA</repository></additional><is_claimable>false</is_claimable><name>Homo sapiens</name><description>Effects of miRNA-mediated TET2 in prostate cancer</description><dates><last_updated>2025-09-24</last_updated><first_public>2015-09-01</first_public></dates><accession>PRJNA275742</accession><cross_references><GEO>GSE66038</GEO><taxon>9606</taxon><PubMed>26404510</PubMed></cross_references></HashMap>