{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Prof. Johannes Loffing, Institute of Anatomy, University of Zurich"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA280721"],"scientific_name":["Mus musculus"],"long_description":["In vitro studies identified TBC1D4 as an regulator of renal ion and water transporting proteins. However, TBC1D4-deficient mice did not show a defective renal salt and water homeostasis. With microarray analysis we aimed to decipher compensatory mechanisms in TBC1D4-deficient mice which might mask the renal phenotype already on transciptomic levels. Overall design: We used and compared mRNA of COPAS-sorted and -enriched distal convoluted tubule (DCT)-cells, known to express TBC1D4 at high levels, of 8-week old male homogenous C57/Bl6 mice of TBC1D4-deficient and wild-type mice."],"tag":["xref:PubMed:26336159"],"repository":["ENA"],"description_synonyms":["Mus musculus, 3.4.22.-, AS160, 5930406J04Rik, Caspase-14 subunit p10, A930035N22, AV295684, Laboratory, Swiss, mice, Mus domesticus, As160, mouse, Swiss Mouse, CASP14, House Mice, Swiss Mice, mini-ICE, Caspase-14 subunit p19, CASP-14, MICE, House Mouse, domesticus, Laboratory Mice, Concept, Kidneys, Role Concept, Roles, House, Mus, Role Concepts, Mini-ICE, Role, Concepts, Mus musculus domesticus, Mouse, house mouse, Mice, Laboratory Mouse, Mus musculus., NIDDM5"],"name_synonyms":["Mus musculus, Laboratory Mice., House, Mus, Laboratory, Swiss, Mus domesticus, mouse, Mus musculus domesticus, Swiss Mouse, mouse <Mus musculus>, Mouse, House Mice, Swiss Mice, house mouse, Mice, Laboratory Mouse, House Mouse, mice C57BL/6xCBA/CaJ hybrid, domesticus, Mus muscaris"],"additional_accession":[]},"is_claimable":false,"name":"Mus musculus","description":"Role of TBC1D4 in mouse kidneys: Identification of compensatory mechanisms in the DCT of TBC1D4-deficient mice","dates":{"last_updated":"2025-09-24","first_public":"2015-04-11"},"accession":"PRJNA280721","cross_references":{"GEO":["GSE67701"],"taxon":["10090"],"PubMed":["26336159"]}}