ENAGenomicsmolecular environmental microbiology Laboratory, molecular microbiology, Korea universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA312967Pseudomonas aeruginosa PAO1Transcriptional profiling in Pseudomonas aeruginosa MPAO1 and its glyoxylate shunt gens transposon insertion mutants (aceA and glcB) was perfomed using microarray analysis with or without 1mM PQ treatment. Based on the gene expression, we investigated role of glyoxylate shunt in P. aeruginosa and found out pathway related with glyoxylate shunt under oxidative stress. Overall design: We performed a transcriptome anaylsis of WT and glyoxylate shunt knockout mutants(aceA and glcB) with or without 1mM PQ treatment. Two independent microarray analysis were done.pathogen:prioritypathogen:bacteriumxref:PubMed:27895125pathogenxref:PubMed:27036942bacteriaENAPseudomonas aeruginosa str. PAO1, Pseudomonas sp. PAO1., Pseudomonas aeruginosa str. PA01, Pseudomonas aeruginosa PA01sodium salt, DNA Oxidative, Oxidative Stress, Antioxidative, immune system tolerance, Antioxidative Stress, Gene, Nitrative Stress, formylformic acid, Anti-oxidative Stresses, Damage, Glyoxalsaeure, Concept, Stresses, Glyoxylsaeure, alpha-ketoacetic acid, 14C2-labeled, Oxidative Nitrative Stress, glyoxylic acid, Role Concept, Drug Tolerance, Immune Tolerance, Oxidative Nitrative, Oxidative DNA, Roles, Oxidative, Stress Injury, Oxidative and Nitrosative Stress, 14C-labeled, Oxidative Nitrative Stresses, Nitro-Oxidative Stress, Role, Concepts, Immunologic Tolerance, Oxidative Cleavages, DNA Oxidative Damages, Nitro-Oxidative Stresses, glyoxalic acid, Oxidative Injury, DNA Damage, Oxidative Damages, study, Oxidative Injuries, Injury, Anti-oxidative Stress, Gene Expressions, DNA Oxidative Damage, Oxidative Cleavage, Cleavage, Oxidative DNA Damages, Expressions, oxoethanoic acid, Anti-oxidative, Nitro-Oxidative, Glyoxylate, Glyoxalate, Oxidative Stress Injuries, Oxidative Stresses, Self Tolerance, oxalaldehydic acid, Tolerance, Anti oxidative Stress, Oxidative DNA Damage, Antioxidative Stresses, glyoxylate, Role Concepts, Stress, calcium salt, 2-(14)C-labeled, Oxidative Stress Injury, Expression, DNA, Nitro Oxidative Stress, Oxidative Damage., drug tolerance, Oxidative Damage, Immunological TolerancefalsePseudomonas aeruginosa PAO1Gene expression-based investigation of a new role for the glyoxylate shunt in contributing to tolerance to oxidative stress.2025-09-242016-02-25PRJNA312967GSE782302089642703694227895125