{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["KRIBB (Korea Research Institute of Bioscience and Biotechnology)"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA315214"],"scientific_name":["Homo sapiens"],"long_description":["To investigate the role for LSD1 in solid cancer cell growth, we depleted LSD1 with siRNA in 50 different cancer cell lines derived from various tissues. By the degree to the cell growth defect mediated by LSD1 knock down, we stratified the cell lines into three groups. Then, to determine differential gene expressions related to the LSD1-dependent cell growth, we performed gene expression microarray analyses of the most and the least LSD1-dependent cell lines. Overall design: Gene expression analysis of 21 cell lines under normal cell culture condition. Determined the gene expression profile of the most and the least LSD1-dependent group by Gene Set Enrichment Analysis (GSEA), and decided to identify the biological pathways correlated with the LSD1 dependence of cell growth."],"repository":["ENA"],"description_synonyms":["HYCC1, Profiling, Carcinoma, Liver, Transcriptome, pulmo, Monitorings, lung parenchyma, Cell Lines, Gene, Cell Carcinoma, Liver Cell, pancreas, adult hepatoma, Hepatomas, Liver Cell Carcinoma, Cell, Gene Expression Profilings, Gene Expression, Differential Display, Transcript Expression Analysis, transcription profiling, Cell Carcinomas, mRNA Differential Displays, Transcript Expression Analyses, Gene Expression Pattern Analysis, HCC, Liver Cell Carcinomas, parenchyma of lung, Gene Expression Monitorings, lung, Line, Adult Liver Cancer, Cell., Adult Liver, Analysis, Profilings, mRNA Differential Display, neoplasm, gene expression profiling, neoplasms, Lines, Carcinomas, Gene Expression Monitoring, DRCTNNB1A, Transcriptome Profiling, Adult Liver Cancers, Hepatocellular carcinoma, Analyses, mRNA, Liver Cancer, Hepatoma, Transcriptome Profilings, adult primary hepatocellular carcinoma, Liver Cancers, HLD5, Transcriptomics, Differential Displays, Cancers, Transcript Expression, Transcriptome Analysis, Adult, Transcriptome Analyses, Monitoring, Hepatocellular Carcinoma, Gene Expression Analysis, Gene Expression Analyses, pulmonary, Hepatocellular, Expression Analysis, Lungs, Hepatocellular Carcinomas, Expression Analyses, Cancer"],"name_synonyms":["Human, Modern., human being, Man (Taxonomy), Homo sapiens, man, Man, human, Modern Man"],"additional_accession":[]},"is_claimable":false,"name":"Homo sapiens","description":"Gene expression profiling in humna HCC, lung, and pancreas cell lines.","dates":{"last_updated":"2025-09-24","first_public":"2016-03-18"},"accession":"PRJNA315214","cross_references":{"GEO":["GSE79232"],"taxon":["9606"]}}