ENAGenomicsWei, School of Life Sciences, University of Science and Technology of Chinahttps://www.ebi.ac.uk/ena/browser/view/PRJNA316426Homo sapiensAntibody-based therapy for cancer is now one of the most successful and important strategies for treating patients with hematological malignancies. However, the lack of efficient tumor-associated antigens restricts the targeting therapy of myeloid leukemia. Analysis of the gene expression profiles of primary bone marrow samples from human acute myeloid leukemia (AML) patients or healthy donors was to identify and expand novel targets for the treatment of myeloid leukemias. we found that epithelial cell adhesion molecule (EpCAM) is overexpressed in patients with AML. Overall design: we analyzed the gene expression profiles of bone marrow mononuclear cells from 2 human acute myeloid leukemia (AML) patients and 2 healthy donors using an oligonucleotide microarray, to identify up-regulated genes in AML samples comparing with healthy tissues.ENAMyelogenous Leukemias, myeloid leukemia, Myelocytic, Myelogenous, leukemia, Chronic Monocytic, myelogenous leukaemia, Leukemia, leukemia granulocytic, Granulocytic Leukemias, myeloid leukaemia, leukaemia granulocytic, Myeloid, leukemia myelogenous, malignant, Monocytic, Monocytic Leukemia, Granulocytic Leukemia, non-lymphoblastic leukaemia, Myelocytic Leukemia, myelocytic leukaemia, granulocytic, Myelogenous Leukemia, myeloid granulocytic leukaemia, leukaemia myelogenous, Leukemias, myelocytic leukemia, Granulocytic, Chronic Monocytic Leukemias, non-lymphocytic leukemia, myeloid granulocytic leukemia., Chronic Monocytic Leukemia, non-lymphocytic leukaemia, leukaemia myeloid, Myeloid Leukemias, leukemia myeloid, Myelocytic Leukemias, Myeloid Leukemia, Chronic, myelogenous leukemia, Non-Lymphocytic Leukemia, Monocytic Leukemias, non-lymphoblastic leukemiaHuman, Modern., human being, Man (Taxonomy), Homo sapiens, man, Man, human, Modern ManfalseHomo sapiensSearch for a novel therapeutic target in myeloid leukemia2025-09-242016-05-15PRJNA316426GSE796059606