ENAGenomicsYonsei Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA319411Mus musculusWe wanted to emphisize the role of intragenic CpG island in various cell differentiation. We especially examined the effect of DNA methyltransferase (DNMT) in the neural differentiation from mouse ES cell. Therefore, we performed the Whole-Genome Bisulfite Sequencing (WGBS) analysis of mouse ES cell, ESC-derived NPC, and also in DNMT double knockout (DKO) conditions. By utilizing these result, we confirmed the genes regulated by intragenic CpG island methylation have effect in NPC differentation.ENADNA MTase MmuIIIA, whole genome bisulfite sequencing, DNA MTase HsaIIIA, DNA methyltransferase HsaIIIA, TBRS, WGBS, DNA methyltransferase MmuIIIA, mESCs, 2.1.1.37, Stem Cells, Bfc., M.MmuIIIA, Dnmt3a, DNMT3A2, Mouse Embryonic Stem Cell, Mouse Embryonic, Mesc, Cells, M.HsaIIIA, Mouse Embryonic Stem, Catnb, mESC, MmuIIIA, whole-genome shotgun bisulfite sequencing, WGSBS, Shotgun bisulfite sequencingMus musculus, Laboratory Mice., House, Mus, Laboratory, Swiss, Mus domesticus, mouse, Mus musculus domesticus, Swiss Mouse, mouse <Mus musculus>, Mouse, House Mice, Swiss Mice, house mouse, Mice, Laboratory Mouse, House Mouse, mice C57BL/6xCBA/CaJ hybrid, domesticus, Mus muscarisfalseMus musculusWGBS of DNMT3A/B DKO mESC and mNPC2025-09-242016-04-25PRJNA31941110090