ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/002/SRR3621862/SRR3621862.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/009/SRR3621869/SRR3621869.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/004/SRR3621864/SRR3621864.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/001/SRR3621871/SRR3621871.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/002/SRR3621872/SRR3621872.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/006/SRR3621866/SRR3621866.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/001/SRR3621861/SRR3621861.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/004/SRR3621874/SRR3621874.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/003/SRR3621863/SRR3621863.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/008/SRR3621868/SRR3621868.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/000/SRR3621870/SRR3621870.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/005/SRR3621865/SRR3621865.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/007/SRR3621867/SRR3621867.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR362/003/SRR3621873/SRR3621873.fastq.gzprimaryOK200GenomicsDr. Noah Shroyer's lab, Baylor College of Medicinehttps://www.ebi.ac.uk/ena/browser/view/PRJNA324264Mus musculusxref:PubMed:28174757We generated three mRNA expression profiles by RNA-Seq of (i) wild-type crypts, (ii) Atoh1 knockout crypts, and (iii) purified ATOH1-positive cells. Overall design: We isolated Atoh1 knockout and littermate wild-type crypts from 6-8 week old Atoh1lox/lox VilCreERT2 and Atoh1lox/WT VilCreERT2 mice, respectively. In addition, ATOH1-positive cells were isolated by flow cytometry of 7AAD-negative (live), GFP-positive cells from either ileal or colonic crypts of Atoh1GFP/GFp mice (which express a functional ATOH1::GFP protein and are phenotypically normal).ENARNA polymerase II core promoter proximal region sequence-specific binding, T-cell leukemia, Materials, wide/broad, MATH-1, adult stage, AGL4, Gene, zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, homeobox 1, Factor, broad, SEPALLATA 2, metal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity, Transcription Factor, Cistrons, Appendix Epiploica, RGD1565171, hindgut, Hath1, transcription factor activity, Small, zinc ion regulated core promoter proximal region sequence-specific DNA binding, large bowel, Taenia Coli, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, Appendix, RNA polymerase II transcription factor activity, HATH1, bHLHa14, Genetic Materials, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity, Omental., metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, Adults, small intestine, Omental Appendices, KNOTTED1-like homeobox gene 5, Genetic Material, adult, F14P3.4, ATH1, Transcription, Omental Appendix, mid intestine, Factors, Genetic, Genomes, F14P3_4, F10N7_150, posterior intestine, Small Intestines, Appendices, whole genome, Omental, metal ion regulated core promoter proximal region sequence-specific binding, copper ion regulated core promoter proximal region sequence-specific binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, small bowel, Transcription factor, F10N7.150, intestinum tenue, Intestines, Math1, wide, anterior intestine, RNA polymerase II proximal promoter sequence-specific DNA binding, Material, COLON, copper ion regulated proximal promoter sequence-specific DNA binding, copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, AGAMOUS-like 4, Cistron, zinc ion regulated proximal promoter sequence-specific DNA binding, sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity, metal ion regulated sequence-specific DNA binding, metal ion regulated proximal promoter sequence-specific DNA binding, TRANSCRIPTION FACTOR, RNA polymerase II distal enhancer sequence-specific binding, Small IntestineMus musculus, Laboratory Mice., House, Mus, Laboratory, Swiss, Mus domesticus, mouse, Mus musculus domesticus, Swiss Mouse, mouse <Mus musculus>, Mouse, House Mice, Swiss Mice, house mouse, Mice, Laboratory Mouse, House Mouse, mice C57BL/6xCBA/CaJ hybrid, domesticus, Mus muscarisfalseMus musculusGenome-wide identification of transcription factor ATOH1 target genes in adult small intestine and colon.2025-09-242017-04-19PRJNA324264GSE821801009028174757