{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/005/SRR4323465/SRR4323465.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/004/SRR4323464/SRR4323464.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/006/SRR4323456/SRR4323456.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/000/SRR4323460/SRR4323460.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/008/SRR4323458/SRR4323458.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/001/SRR4323461/SRR4323461.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/007/SRR4323457/SRR4323457.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/002/SRR4323462/SRR4323462.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/003/SRR4323463/SRR4323463.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/009/SRR4323459/SRR4323459.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Stress Neurobiology and Neurogenetics, Max-Planck-Institute of Psychiatry"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA345045"],"scientific_name":["Mus musculus"],"tag":["xref:PubMed:27829158"],"long_description":["MicroRNAs are important regulators of gene expression and associated with stress-related psychiatric disorders. We report that exposing mice to chronic stress led to a specific increase in microRNA-15a levels in the amygdala-Ago2 complex, and a concomitant reduction in the levels of its predicted target, FKBP51, which is implicated in stress-related psychiatric disorders. Reciprocally, mice expressing reduced levels of amygdalar microRNA-15a following exposure to chronic stress exhibited increased anxiety-like behaviors. Here, we performed small RNA Sequencing of mouse basolateral amygdala after miR15a knockdown using injection of a miR-15a sponge virus or control sponge virus. Overall design: Small RNA Sequencing of basolateral amygdala of 5 mice injected with a miR-15a sponge virus and 5 mice injected with a control sponge virus."],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Mus musculus","description":"Small RNA Sequencing of mouse amygdala after knockdown of miR-15a","dates":{"last_updated":"2025-09-24","first_public":"2016-10-02"},"accession":"PRJNA345045","cross_references":{"GEO":["GSE87533"],"taxon":["10090"],"PubMed":["27829158"]}}