ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/005/SRR4323465/SRR4323465.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/004/SRR4323464/SRR4323464.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/006/SRR4323456/SRR4323456.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/000/SRR4323460/SRR4323460.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/008/SRR4323458/SRR4323458.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/001/SRR4323461/SRR4323461.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/007/SRR4323457/SRR4323457.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/002/SRR4323462/SRR4323462.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/003/SRR4323463/SRR4323463.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR432/009/SRR4323459/SRR4323459.fastq.gzprimaryOK200GenomicsStress Neurobiology and Neurogenetics, Max-Planck-Institute of Psychiatryhttps://www.ebi.ac.uk/ena/browser/view/PRJNA345045Mus musculusxref:PubMed:27829158MicroRNAs are important regulators of gene expression and associated with stress-related psychiatric disorders. We report that exposing mice to chronic stress led to a specific increase in microRNA-15a levels in the amygdala-Ago2 complex, and a concomitant reduction in the levels of its predicted target, FKBP51, which is implicated in stress-related psychiatric disorders. Reciprocally, mice expressing reduced levels of amygdalar microRNA-15a following exposure to chronic stress exhibited increased anxiety-like behaviors. Here, we performed small RNA Sequencing of mouse basolateral amygdala after miR15a knockdown using injection of a miR-15a sponge virus or control sponge virus. Overall design: Small RNA Sequencing of basolateral amygdala of 5 mice injected with a miR-15a sponge virus and 5 mice injected with a control sponge virus.ENAfalseMus musculusSmall RNA Sequencing of mouse amygdala after knockdown of miR-15a2025-09-242016-10-02PRJNA345045GSE875331009027829158